Invasive fungal infections pose an important threat to public health and are an under-
recognized component of antimicrobial resistance, an emerging crisis worldwide. Across a …

Key Points Cryptococcal Disease in Diverse Hosts Worldwide, cryptococcal meningitis kills
up to 180,000 persons annually and is the most common cause of nonviral meningitis in the …

Prior to the SARS-CoV-2 pandemic, antibiotic resistance was listed as the major global
health care priority. Some analyses, including the O'Neill report, have predicted that deaths …

Cryptococcosis is a major worldwide disseminated invasive fungal infection. Cryptococcosis,
particularly in its most lethal manifestation of cryptococcal meningitis, accounts for …

Background Cryptococcal meningitis is a leading cause of human immunodeficiency virus
(HIV)–related death in sub-Saharan Africa. Whether a treatment regimen that includes a …

Cryptococcus neoformans and Cryptococcus gattii species complexes cause
meningoencephalitis with high fatality rates and considerable morbidity, particularly in …

Cryptococcus spp., in particular Cryptococcus neoformans and Cryptococcus gattii, have an
enormous impact on human health worldwide. The global burden of cryptococcal meningitis …

Cryptococcosis is an infectious disease caused by the encapsulated fungi Cryptococcus
neoformans and Cryptococcus gattii. Cryptococcal infection can develop in apparently …

Human fungal infections are a historically neglected area of disease research, yet they
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …

Pulmonary cryptococcosis is an important opportunistic invasive mycosis in
immunocompromised patients, but it is also increasingly seen in immunocompetent patients …