Applications of focused ultrasound in the brain: from thermoablation to drug delivery
Focused ultrasound (FUS) is a disruptive medical technology, and its implementation in the
clinic represents the culmination of decades of research. Lying at the convergence of …
clinic represents the culmination of decades of research. Lying at the convergence of …
Reactive oxygen species (ROS)-based nanomedicine
B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …
Non-invasive transcranial ultrasound stimulation for neuromodulation
Transcranial ultrasound stimulation (TUS) holds great potential as a tool to alter neural
circuits non-invasively in both animals and humans. In contrast to established non-invasive …
circuits non-invasively in both animals and humans. In contrast to established non-invasive …
[HTML][HTML] Ultrasound neuromodulation: a review of results, mechanisms and safety
Ultrasonic neuromodulation is a rapidly growing field, in which low-intensity ultrasound (US)
is delivered to nervous system tissue, resulting in transient modulation of neural activity. This …
is delivered to nervous system tissue, resulting in transient modulation of neural activity. This …
High-intensity focused ultrasound: a review of mechanisms and clinical applications
Abstract High Intensity Focused Ultrasound (HIFU) is an emerging and increasingly useful
modality in the treatment of cancer and other diseases. Although traditional use of …
modality in the treatment of cancer and other diseases. Although traditional use of …
Ultrasound technologies for imaging and modulating neural activity
Visualizing and perturbing neural activity on a brain-wide scale in model animals and
humans is a major goal of neuroscience technology development. Established electrical and …
humans is a major goal of neuroscience technology development. Established electrical and …
Focused ultrasound excites cortical neurons via mechanosensitive calcium accumulation and ion channel amplification
Ultrasonic neuromodulation has the unique potential to provide non-invasive control of
neural activity in deep brain regions with high spatial precision and without chemical or …
neural activity in deep brain regions with high spatial precision and without chemical or …
Intrinsic functional neuron-type selectivity of transcranial focused ultrasound neuromodulation
Transcranial focused ultrasound (tFUS) is a promising neuromodulation technique, but its
mechanisms remain unclear. We hypothesize that if tFUS parameters exhibit distinct …
mechanisms remain unclear. We hypothesize that if tFUS parameters exhibit distinct …
Ectopic expression of a mechanosensitive channel confers spatiotemporal resolution to ultrasound stimulations of neurons for visual restoration
S Cadoni, C Demené, I Alcala, M Provansal… - Nature …, 2023 - nature.com
Remote and precisely controlled activation of the brain is a fundamental challenge in the
development of brain–machine interfaces for neurological treatments. Low-frequency …
development of brain–machine interfaces for neurological treatments. Low-frequency …
Manipulation of subcortical and deep cortical activity in the primate brain using transcranial focused ultrasound stimulation
The causal role of an area within a neural network can be determined by interfering with its
activity and measuring the impact. Many current reversible manipulation techniques have …
activity and measuring the impact. Many current reversible manipulation techniques have …