Molecular biomarkers in urothelial carcinoma of the bladder: are we there yet?

GJ Netto - Nature Reviews Urology, 2012 - nature.com
The unprecedented advances in cancer genetics and genomics are rapidly affecting the
clinical management of solid tumors. Molecular diagnostics are now an integral part of …

Update for the practicing pathologist: The International Consultation On Urologic Disease-European association of urology consultation on bladder cancer

MB Amin, SC Smith, VE Reuter, JI Epstein… - Modern …, 2015 - nature.com
Abstract The International Consultations on Urological Diseases are international
consensus meetings, supported by the World Health Organization and the Union …

TERT Promoter Mutations Occur Early in Urothelial Neoplasia and Are Biomarkers of Early Disease and Disease Recurrence in Urine

I Kinde, E Munari, SF Faraj, RH Hruban… - Cancer …, 2013 - aacrjournals.org
Activating mutations occur in the promoter of the telomerase reverse transcriptase (TERT)
gene in 66% of muscle-invasive urothelial carcinomas. To explore their role in bladder …

Assessment of tumoral PD-L1 expression and intratumoral CD8+ T cells in urothelial carcinoma

SF Faraj, E Munari, G Guner, J Taube, R Anders… - Urology, 2015 - Elsevier
Objective To evaluate programmed death ligand 1 (PD-L1) expression in urothelial
carcinoma of the bladder in relationship with tumor-infiltrating CD8+ T cells. Materials and …

Histologic grading of urothelial carcinoma: a reappraisal

L Cheng, GT MacLennan, A Lopez-Beltran - Human pathology, 2012 - Elsevier
A uniform grading system for bladder cancer will allow for valid comparison of treatment
results among different centers. The introduction of the World Health Organization …

[HTML][HTML] Molecular oncology of bladder cancer from inception to modern perspective

SD Lokeshwar, M Lopez, S Sarcan, K Aguilar… - Cancers, 2022 - mdpi.com
Simple Summary Bladder cancer (BC) is a common cancer that causes high morbidity and
mortality among affected patients. As a carcinogen-driven cancer, molecular oncology of BC …

Bladder carcinoma data with clinical risk factors and molecular markers: a cluster analysis

E Redondo-Gonzalez, LN de Castro… - BioMed research …, 2015 - Wiley Online Library
Bladder cancer occurs in the epithelial lining of the urinary bladder and is amongst the most
common types of cancer in humans, killing thousands of people a year. This paper is based …

Quantitative CT texture analysis for evaluating histologic grade of urothelial carcinoma

GMY Zhang, H Sun, B Shi, ZY **, HD Xue - Abdominal radiology, 2017 - Springer
Purpose To investigate the feasibility of using CT texture analysis (CTTA) to differentiate
between low-versus high-grade urothelial carcinoma. Methods A total of 105 patients with …

Significant role of lifetime cigarette smoking in worsening bladder cancer and upper tract urothelial carcinoma prognosis: a meta-analysis

FHM van Osch, SHJ Jochems, FJ van Schooten… - The Journal of …, 2016 - Elsevier
Purpose Although cigarette smoking is a well established risk factor for urothelial cancer, its
role in urothelial cancer prognosis is still undetermined. In this meta-analysis we quantify the …

Significance of a minor high-grade component in a low-grade noninvasive papillary urothelial carcinoma of bladder

LO Reis, D Taheri, A Chaux, G Guner, MAM Rodriguez… - Human pathology, 2016 - Elsevier
To assess the clinicopathological features and prognostic significance of the presence of 5%
or less high-grade component in otherwise low-grade noninvasive bladder urothelial …