Three-dimensional multicellular spheroids (MCSs) have a complex architectural structure,
dynamic cell–cell/cell–matrix interactions and bio-mimicking in vivo microenvironment. As a …

Microdroplets in microfluidics offer a great number of opportunities in chemical and
biological research. They provide a compartment in which species or reactions can be …

In the last two decades, microfluidics has emerged as a powerful tool of high precision and
versatility, mainly applied to biomedicine. As a result of its strengths, the literature …

The encapsulation of living cells in a variety of soft polymers or hydrogels is important,
particularly, for the rehabilitation of functional tissues capable of repairing or replacing …

Most cell biology experiments are performed in bulk cell suspensions where cell secretions
become diluted and mixed in a contiguous sample. Confinement of single cells to small …

Due to their hydrophilic, biocompatible, and highly tunable nature, hydrogel materials have
attracted strong interest in the recent years for numerous biotechnological applications. In …

Cell and islet microencapsulation in synthetic hydrogels provide an immunoprotective and
cell-supportive microenvironment. A microfluidic strategy for the genaration of …

Microstructured devices are widely used for manufacturing products that benefit from
process intensification, with pharmaceutical products or specialties of the chemical industry …

Channel-fouling is a pervasive problem in continuous flow chemistry, causing poor product
control and reactor failure. Droplet chemistry, in which the reaction mixture flows as discrete …

Microfluidic droplet-on-demand systems allow the controllable construction of multiple
droplets of previously unattainable morphologies. Guided by the diagrams of the possible …