Time to give up on cardioprotection? A critical appraisal of clinical studies on ischemic pre-, post-, and remote conditioning

G Heusch, T Rassaf - Circulation research, 2016 - Am Heart Assoc
The mortality from acute myocardial infarction (AMI) remains significant, and the prevalence
of post-myocardial infarction heart failure is increasing. Therefore, cardioprotection beyond …

Ischaemic preconditioning–Current knowledge and potential future applications after 30 years of experience

K Stokfisz, A Ledakowicz-Polak, M Zagorski… - Advances in medical …, 2017 - Elsevier
Ischaemic preconditioning (IPC) phenomenon has been known for thirty years. During that
time several studies showed that IPC provided by brief ischaemic and reperfusion episodes …

Remote ischemic conditioning and cardioprotection: a systematic review and meta-analysis of randomized clinical trials

S Le Page, T Bejan-Angoulvant, D Angoulvant… - Basic research in …, 2015 - Springer
Remote ischemic conditioning (RIC) represents an innovative cardioprotective method that
has been investigated in numerous clinical studies providing miscellaneous results. This …

Remote ischemic preconditioning reduces myocardial injury in patients undergoing coronary stent implantation

SJ Luo, YJ Zhou, DM Shi, HL Ge, JL Wang… - Canadian Journal of …, 2013 - Elsevier
Background Myocardial necrosis occurs frequently in elective percutaneous coronary
intervention (PCI) and is associated with subsequent major adverse cardiovascular events …

Remote ischaemic conditioning: cardiac protection from afar

V Sivaraman, JMJ Pickard, DJ Hausenloy - Anaesthesia, 2015 - Wiley Online Library
For patients with ischaemic heart disease, remote ischaemic conditioning may offer an
innovative, non‐invasive and virtually cost‐free therapy for protecting the myocardium …

From protecting the heart to improving athletic performance–the benefits of local and remote ischaemic preconditioning

V Sharma, R Marsh, B Cunniffe, M Cardinale… - … drugs and therapy, 2015 - Springer
Abstract Remote Ischemic Preconditioning (RIPC) is a non-invasive cardioprotective
intervention that involves brief cycles of limb ischemia and reperfusion. This is typically …

Remote ischemic postconditioning for ischemic stroke: a systematic review and meta-analysis of randomized controlled trials

JJ Zhao, H **ao, WB Zhao, XP Zhang… - Chinese Medical …, 2018 - mednexus.org
Background: Remote ischemic postconditioning (RIPostC) appears to protect distant organs
from ischemia-reperfusion injury (IRI). However, cerebral protection results have remained …

Remote ischemic preconditioning reduces perioperative cardiac and renal events in patients undergoing elective coronary intervention: a meta-analysis of 11 …

H Pei, Y Wu, Y Wei, Y Yang, S Teng, H Zhang - PloS one, 2014 - journals.plos.org
Background Results from randomized controlled trials (RCT) concerning cardiac and renal
effect of remote ischemic preconditioning (RIPC) in patients with stable coronary artery …

[HTML][HTML] Cardioprotection by remote ischemic conditioning: mechanisms and clinical evidences

A Aimo, C Borrelli, A Giannoni… - World journal of …, 2015 - ncbi.nlm.nih.gov
In remote ischemic conditioning (RIC), several cycles of ischemia and reperfusion render
distant organ and tissues more resistant to the ischemia-reperfusion injury. The intermittent …

Effect of remote ischemic preconditioning in the elderly patients with coronary artery disease with diabetes mellitus undergoing elective drug-eluting stent implantation

X Xu, Y Zhou, S Luo, W Zhang, Y Zhao, M Yu… - …, 2014 - journals.sagepub.com
There is conflicting evidence regarding the effectiveness of remote ischemic preconditioning
(RIPC) in patients undergoing elective percutaneous coronary intervention (PCI). Therefore …