Genomic data are becoming increasingly affordable and easy to collect, and new tools for
their analysis are appearing rapidly. Conservation biologists are interested in using this …

Deleterious genetic variation is abundant in wild populations, and understanding the
ecological and conservation implications of such variation is an area of active research …

Understanding the factors that cause endangered populations to either grow or decline is
crucial for preserving biodiversity. Conservation efforts often address extrinsic threats, such …

Genomic structural variants (SVs) play a crucial role in adaptive evolution, yet their average
fitness effects and characterization with pangenome tools are understudied in wild animal …

Simulation is a key tool in population genetics for both methods development and empirical
research, but producing simulations that recapitulate the main features of genomic datasets …

Typically much smaller in number than their mainland counterparts, island populations are
ideal systems to investigate genetic threats to small populations. The Svalbard reindeer …

Dominance refers to the effect of a heterozygous genotype relative to that of the two
homozygous genotypes. The degree of dominance of mutations for fitness can have a …

A few iconic examples have proven the value of facilitated gene flow for counteracting
inbreeding depression and staving off extinction; yet, the practice is often not implemented …

Island ecosystems provide natural laboratories to assess the impacts of isolation on
population persistence. However, most studies of persistence have focused on a single …

Increased human activities caused the isolation of populations in many species—often
associated with genetic depletion and negative fitness effects. The effects of isolation are …