PVT1 lncRNA in lung cancer: A key player in tumorigenesis and therapeutic opportunities
The lncRNA PVT1 has emerged as a pivotal component in the intricate landscape of cancer
pathogenesis, particularly in lung cancer. PVT1, situated in the 8q24 chromosomal region …
pathogenesis, particularly in lung cancer. PVT1, situated in the 8q24 chromosomal region …
Crosstalk of lncRNA and cellular metabolism and their regulatory mechanism in cancer
YH Lin - International journal of molecular sciences, 2020 - mdpi.com
The imbalanced regulation of metabolic homeostasis and energy production is highly
associated with inflammation, tumor growth, metastasis and cancer progression. Both …
associated with inflammation, tumor growth, metastasis and cancer progression. Both …
Exosomal lncRNA PVT1/VEGFA axis promotes colon cancer metastasis and stemness by downregulation of tumor suppressor miR‐152‐3p
Background. Treating advanced colon cancer remains challenging in clinical settings
because of the development of drug resistance and distant metastasis. Mechanisms …
because of the development of drug resistance and distant metastasis. Mechanisms …
PVT1 inhibition stimulates anti-tumor immunity, prevents metastasis, and depletes cancer stem cells in squamous cell carcinoma
Z Qin, W Zhang, S Liu, Y Wang, X Peng, L Jia - Cell Death & Disease, 2023 - nature.com
Cancer stem cells (CSCs) cause tumor metastasis and immune evasion by as-yet-unknown
molecular mechanisms. In the present study, we identify a long noncoding RNA (lncRNA) …
molecular mechanisms. In the present study, we identify a long noncoding RNA (lncRNA) …
LncRNAs has been identified as regulators of Myeloid-derived suppressor cells in lung cancer
Y Liu, Y Han, Y Zhang, T Lv, X Peng… - Frontiers in …, 2023 - frontiersin.org
Lung tumours are widespread pathological conditions that attract much attention due to their
high incidence of death. The immune system contributes to the progression of these …
high incidence of death. The immune system contributes to the progression of these …
Integrative genomic analyses identify lncRNA regulatory networks across pediatric leukemias and solid tumors
A Modi, G Lopez, KL Conkrite, C Su, TC Leung… - Cancer research, 2023 - AACR
Long noncoding RNAs (lncRNA) play an important role in gene regulation and contribute to
tumorigenesis. While pan-cancer studies of lncRNA expression have been performed for …
tumorigenesis. While pan-cancer studies of lncRNA expression have been performed for …
LncRNA PVT1: as a therapeutic target for breast cancer
KJ Baljon, P Ramaiah, EAM Saleh, F Al-Dolaimy… - … -Research and Practice, 2023 - Elsevier
A significant number of women are identified with breast cancer (BC) every year, making it
among the most prevalent malignancies and one of the leading causes of mortality globally …
among the most prevalent malignancies and one of the leading causes of mortality globally …
Association of MALAT1 and PVT1 variants, expression profiles and target miRNA-101 and miRNA-186 with colorectal cancer: correlation with epithelial-mesenchymal …
The influence of PVT1 and MALAT1 variants on colorectal cancer (CRC) susceptibility and
their impact on PVT1/miRNA-186/epithelial-mesenchymal transition (EMT) and …
their impact on PVT1/miRNA-186/epithelial-mesenchymal transition (EMT) and …
Diagnostic and therapeutic implications of long non-coding rnas in leukemia
Simple Summary Research on leukemia has often led to novel approaches in clinical
practice. Cytogenetical and molecular markers have been introduced in treatment protocols …
practice. Cytogenetical and molecular markers have been introduced in treatment protocols …
lncRNAs as prognostic markers and therapeutic targets in cuproptosis-mediated cancer
Long non-coding RNAs (lncRNAs) have emerged as crucial regulators in various cellular
processes, including cancer progression and stress response. Recent studies have …
processes, including cancer progression and stress response. Recent studies have …