Reversible addition–fragmentation chain transfer (RAFT) is one of the most robust and
versatile methods for controlling radical polymerization. With appropriate selection of the …

Highlights•Minor modifications to polymer structure determine transfection
properties.•Efficient gene delivery requires timely release of DNA.•Serum stability is …

RAFT-mediated polymerization, providing control over polymer length and architecture as
well as facilitating post polymerization modification of end groups, has been applied to …

One effective strategy in the field of biomaterials is to develop biomimetic interfaces to
modulate the cell behavior and promote tissue regeneration and surface modification is the …

Polymeric nanoparticles have shown great promise as attractive vehicles for drug delivery.
In this study, we designed, prepared and characterized biodegradable amphiphilic triblock …

A series of thermoresponsive diblock copolymers of poly [2-(dimethylamino) ethyl
methacrylate-block-di (ethyleneglycol) methyl ether methacrylate], poly (DMAEMA-b …

Cationic polymers are widely used materials in diverse biotechnologies. Subtle variations in
these polymers' properties can change them from exceptional delivery agents to toxic …

The rational design of effective and safe non-viral gene vectors is largely dependent on the
understanding of the structure–property relationship. We herein report the design of a new …

Poly (γ-4-((2-(piperidin-1-yl) ethyl) aminomethyl) benzyl-l-glutamate)(PPABLG), a cationic
helical polypeptide, has been recently developed by us as an effective non-viral gene …

High-grade serous ovarian cancer (HGSOC) is the most lethal gynaecological malignancy.
Most patients are diagnosed at late stages when the tumour has metastasised throughout …