Lung-resident memory B cells (BRM cells) are elicited after influenza infections of mice, but
connections to other pathogens and hosts—as well as their functional significance—have …

A crisis in bacterial infections looms as ageing populations, increasing rates of bacteraemia
and healthcare-associated infections converge with increasing antimicrobial resistance and …

Postpartum hemorrhage (PPH) is usually caused by obstetrical complications but may be
exacerbated by hemostatic impairment. Standard laboratory tests of coagulation often take …

Summary Background Pneumococcal conjugate vaccines (PCVs) induce serotype-specific
IgG antibodies, effectively reducing vaccine-serotype carriage and invasive pneumococcal …

Community-acquired pneumonia is a widespread disease with significant morbidity and
mortality. Alveolar macrophages are tissue-resident lung cells that play a crucial role in …

Background With the successful implementation of the Surviving Sepsis Campaign
guidelines, post-sepsis in-hospital mortality to sepsis continues to decrease. Those who …

Recovery from respiratory pneumococcal infections generates lung-localized protection
against heterotypic bacteria, mediated by resident memory lymphocytes. Optimal protection …

Streptococcus pneumoniae is a major cause of community-acquired pneumonia,
bacteremia, and meningitis in older adults worldwide. Two pneumococcal vaccines …

Abstract Acute Otitis Media (AOM) is a multifactorial disease occurring mostly in young
children who are immunologically naïve to AOM pathogens. This review focuses on work …

Streptococcus pneumoniae (Spn) is a bacterial pathogen known to colonize the upper
respiratory tract and cause serious opportunistic diseases such as pneumonia, bacteremia …