Abstract Staining with Congo Red (CR) is a qualitative method used for the identification of
amyloids in vitro and in tissue sections. However, the drawbacks and artefacts obtained …

In this narrative review, the biological/biochemical impact (toxicity) of a large array of known
individual uremic retention solutes and groups of solutes is summarized. We classified these …

Citrate synthase is a key mitochondrial enzyme that utilizes acetyl-CoA and oxaloacetate to
form citrate in the mitochondrial membrane, which participates in energy production in the …

Acute and chronic kidney disease continues to confer significant morbidity and mortality in
the clinical setting. Despite high prevalence of these conditions, few validated biomarkers …

In this study, fibrillation of soybean protein isolate (SPI) and β-conglycinin (7S)/glycinin (11S)
in acid-heating with CaCl 2 concentration (0–200 mM) was explored. Fibril formation kinetics …

The use of buffers that mimic biological solutions is a foundation of biochemical and
biophysical studies. However, buffering agents have both specific and nonspecific …

Background Understanding Aβ aggregation and inhibiting it at early stages is of utmost
importance in treating Alzheimer's and other related amyloidogenic diseases. However …

A comparative study of amyloid properties of the aggregates of smooth muscle titin (SMT)
from chicken gizzard was carried out. These aggregates were formed in two solutions: 0.15 …

The newly synthesized unfolded polypeptide attains its functional and unique three-
dimensional conformation through the process of protein folding for which several models …

β-2-Microglobulin (β2m) forms amyloid fibrils in the joints of patients undergoing dialysis
treatment as a result of kidney failure. One of the ways in which β2m can be induced to form …