Importance Questions of whether and how cortical thickness (CTh) alterations differ over the
course of schizophrenia (SCZ) have yet to be resolved. Objective To characterize CTh …

Despite hundreds of structural MRI studies documenting smaller brain volumes on average
in schizophrenia compared to controls, little attention has been paid to group differences in …

Bipolar disorder (BP) is a chronic neuropsychiatric condition characterized by pathological
fluctuations in mood from mania to depression. Adoption, twin and family studies have …

Objective: Cortical thickness reductions in schizophrenia are irregularly distributed across
multiple loci. The authors hypothesized that cortical connectivity networks would explain the …

Background Peripheral inflammation is implicated in schizophrenia, however, not all
individuals demonstrate inflammatory alterations. Recent studies identified inflammatory …

Although schizophrenia is a brain disorder, increasing evidence suggests that there may be
body-wide involvement in this illness. However, direct evidence of brain structures involved …

Manual tracing of magnetic resonance imaging (MRI) represents the gold standard for
segmentation in clinical neuropsychiatric research studies, however automated approaches …

The location, extent and progression of longitudinal morphometric changes after first-
episode of psychosis (FEP) remains unclear. We investigated ventricular and cortico …

There has been a substantial amount of research reporting the neuroanatomical
associations of psychotic symptoms in people with schizophrenia. Comparatively little …

Background Major depressive disorder (MDD) and schizophrenia (SCZ) are heritable brain
disorders characterized by alterations in cortical thickness. However, the shared genetic …