Non-coding RNAs and potential therapeutic targeting in cancer
Recent advances have begun to clarify the physiological and pathological roles of non-
coding RNAs (ncRNAs) in various diseases, including cancer. Among these, microRNAs …
coding RNAs (ncRNAs) in various diseases, including cancer. Among these, microRNAs …
MicroRNA-34 family: a potential tumor suppressor and therapeutic candidate in cancer
Abstract MicroRNA-34 (miR-34) has been reported to be dysregulated in various human
cancers and regarded as a tumor suppressive microRNA because of its synergistic effect …
cancers and regarded as a tumor suppressive microRNA because of its synergistic effect …
Structure and function of cationic and ionizable lipids for nucleic acid delivery
Hereditary genetic diseases, cancer, and infectious diseases are affecting global health and
become major health issues, but the treatment development remains challenging. Gene …
become major health issues, but the treatment development remains challenging. Gene …
Mir-34: a new weapon against cancer?
The microRNA (miRNA)-34a is a key regulator of tumor suppression. It controls the
expression of a plethora of target proteins involved in cell cycle, differentiation and …
expression of a plethora of target proteins involved in cell cycle, differentiation and …
miR-221/222 as biomarkers and targets for therapeutic intervention on cancer and other diseases: A systematic review
Among deregulated microRNAs (miRs) in human malignancies, miR-221 has been widely
investigated for its oncogenic role and as a promising biomarker. Moreover, recent evidence …
investigated for its oncogenic role and as a promising biomarker. Moreover, recent evidence …
Targeting microRNAs in cancer gene therapy
W Ji, B Sun, C Su - Genes, 2017 - mdpi.com
MicroRNAs (miRNAs) are a kind of conserved small non-coding RNAs that participate in
regulating gene expression by targeting multiple molecules. Early studies have shown that …
regulating gene expression by targeting multiple molecules. Early studies have shown that …
MiR‐182‐3p targets TRF2 and impairs tumor growth of triple‐negative breast cancer
R Dinami, L Pompili, E Petti, M Porru… - EMBO Molecular …, 2023 - embopress.org
The telomeric repeat‐binding factor 2 (TRF2) is a telomere‐cap** protein that plays a key
role in the maintenance of telomere structure and function. It is highly expressed in different …
role in the maintenance of telomere structure and function. It is highly expressed in different …
miRNAs and lncRNAs as novel therapeutic targets to improve cancer immunotherapy
Simple Summary Cancer onset and progression are promoted by high deregulation of the
immune system. Recently, major advances in molecular and clinical cancer immunology …
immune system. Recently, major advances in molecular and clinical cancer immunology …
Lipid nanocarriers for microRNA delivery
Non-coding RNAs (ncRNAs) like microRNAs (miRNAs) or small interference RNAs (siRNAs)
with their power to selectively silence any gene of interest enable the targeting of so far …
with their power to selectively silence any gene of interest enable the targeting of so far …
IGF2BP3 functions as a potential oncogene and is a crucial target of miR-34a in gastric carcinogenesis
Background Gastric cancer (GC) is one of the frequent causes of cancer-related death in
eastern Asian population. IGF2BP2 lists in the top rank up-regulated genes in GC, but its …
eastern Asian population. IGF2BP2 lists in the top rank up-regulated genes in GC, but its …