Renal cell carcinoma: histological classification and correlation with imaging findings

VF Muglia, A Prando - Radiologia brasileira, 2015 - SciELO Brasil
Renal cell carcinoma (RCC) is the seventh most common histological type of cancer in the
Western world and has shown a sustained increase in its prevalence. The histological …

Understanding pathologic variants of renal cell carcinoma: distilling therapeutic opportunities from biologic complexity

B Shuch, A Amin, AJ Armstrong, JN Eble, V Ficarra… - European urology, 2015 - Elsevier
Context Once believed to represent a uniform malignant phenotype, renal cell carcinoma
(RCC) is now viewed as a diverse group of cancers that arise from the nephron. Objective …

Kidney cancer, version 3.2022, NCCN clinical practice guidelines in oncology

RJ Motzer, E Jonasch, N Agarwal, A Alva… - Journal of the National …, 2022 - jnccn.org
The NCCN Guidelines for Kidney Cancer focus on the screening, diagnosis, staging,
treatment, and management of renal cell carcinoma (RCC). Patients with relapsed or stage …

The International Society of Urological Pathology (ISUP) vancouver classification of renal neoplasia

JR Srigley, B Delahunt, JN Eble, L Egevad… - The American journal …, 2013 - journals.lww.com
The classification working group of the International Society of Urological Pathology
consensus conference on renal neoplasia was in charge of making recommendations …

Kidney cancer, version 2.2017, NCCN clinical practice guidelines in oncology

RJ Motzer, E Jonasch, N Agarwal, S Bhayani… - Journal of the National …, 2017 - jnccn.org
The NCCN Guidelines for Kidney Cancer provide multidisciplinary recommendations for the
clinical management of patients with clear cell and non–clear cell renal carcinoma. These …

The International Society of Urological Pathology (ISUP) grading system for renal cell carcinoma and other prognostic parameters

B Delahunt, JC Cheville, G Martignoni… - The American journal …, 2013 - journals.lww.com
Abstract The International Society of Urological Pathology 2012 Consensus Conference
made recommendations regarding classification, prognostic factors, staging, and …

Renal cell carcinoma

P Cairns - Cancer biomarkers, 2011 - content.iospress.com
Abstract Renal Cell Carcinoma (RCC) has the highest mortality rate of the genitourinary
cancers and the incidence of RCC has risen steadily. If detected early, RCC is curable by …

Regulation of TFEB and V‐ATPases by mTORC1

S Peña‐Llopis, S Vega‐Rubin‐de‐Celis… - The EMBO …, 2011 - embopress.org
Mammalian target of rapamycin (mTOR) complex 1 (mTORC1) is an important, highly
conserved, regulator of cell growth. Ancient among the signals that regulate mTORC1 are …

WHO/ISUP classification, grading and pathological staging of renal cell carcinoma: standards and controversies

AY Warren, D Harrison - World journal of urology, 2018 - Springer
Purpose Pathological parameters assessed on biopsies and resection specimens have a
pivotal role in the diagnosis, prognosis and management of patients with renal cell …

Multistep regulation of TFEB by MTORC1

S Vega-Rubin-de-Celis, S Peña-Llopis, M Konda… - Autophagy, 2017 - Taylor & Francis
The master regulator of lysosome biogenesis, TFEB, is regulated by MTORC1 through
phosphorylation at S211, and a S211A mutation increases nuclear localization. However …