Ataxia is a neurodegenerative syndrome, which can emerge as a major element of a
disease or represent a symptom of more complex multisystemic disorders. It comprises …

Spinocerebellar ataxias (SCAs) comprise a heterogeneous group of autosomal dominant
disorders. The relative frequency of the different SCA subtypes varies broadly among …

Abstract Spinocerebellar ataxias type 3 (SCA3) and type 10 (SCA10) are the most prevalent
in southern Brazil. To analyze the relationships between volumetric MRI changes and …

Spinocerebellar ataxia type 10 (SCA10) is characterized by progressive cerebellar
neurodegeneration and, in many patients, epilepsy. This disease mainly occurs in …

Esophageal squamous cell carcinoma (ESCC) is an invasive malignant tumor with a high
incidence rate and mortality. It is imperative to study its tumorigenesis and development for …

Summary Spinocerebellar ataxia type 10 (SCA10) is an autosomal-dominant disorder
caused by an expanded pentanucleotide repeat in the ATXN10 gene. This repeat …

Pentanucleotide expansion diseases constitute a special class of neurodegeneration. The
repeat expansions occur in non-coding regions, have likely arisen from Alu elements, and …

Recent findings suggest a significant effect of the cerebellar circuit deterioration on the
clinical manifestation of Huntington's disease, calling for a better understanding of the …

Gluten ataxia is a rare immune-mediated neurological disorder caused by the ingestion of
gluten. The diagnosis is not straightforward as antibodies are present in only up to 38% of …

Background Spinocerebellar ataxia type 10 is a neurodegenerative disorder caused by the
expansion of an ATTCT pentanucleotide repeat. Its clinical features include ataxia and, in …