The fruit fly, Drosophila melanogaster, has been used to understand fundamental principles
of genetics and biology for over a century. Drosophila is now also considered an essential …

Drosophila has been the invertebrate model organism of choice for the study of innate
immune responses during the past few decades. Many Drosophila–microbe interaction …

Epithelial immunity protects the host from harmful microbial invaders but also controls the
beneficial microbiota on epithelial surfaces. When this delicate balance between pathogen …

Increasing antibiotic resistance of bacterial pathogens poses a serious threat to human
health worldwide. Methicillin-resistant Staphylococcus aureus (MRSA) is among the most …

Drug discovery is a complex process, and the use of a comprehensive approach is deemed
necessary to discover new chemical entities with novel mechanisms of action. This research …

Background: Polymicrobial infections are complex infections associated with worse
outcomes compared to monomicrobial infections. We need simple, fast, and cost-effective …

The Epstein-Barr virus (EBV) commonly infects humans and is highly associated with
different types of cancers and autoimmune diseases. EBV has also been detected in …

Introduction: The emergence of antibiotic-resistant Staphylococcus aureus is a major threat
for worldwide communities. To overcome such serious problem, the discovery of novel …

Given the increasing concern about antimicrobial resistance among the microorganisms that
cause infections in our society, there is an urgent need for new drug discovery. Currently …

We exploited bacterial infection assays using the fruit fly Drosophila melanogaster to identify
anti-infective compounds that abrogate the pathological consequences in the infected hosts …