Choroid plexus and the blood–cerebrospinal fluid barrier in disease

P Solár, A Zamani, L Kubíčková, P Dubový… - Fluids and Barriers of the …, 2020 - Springer
The choroid plexus (CP) forming the blood–cerebrospinal fluid (B-CSF) barrier is among the
least studied structures of the central nervous system (CNS) despite its clinical importance …

Multiplicity of cerebrospinal fluid functions: New challenges in health and disease

CE Johanson, JA Duncan, PM Klinge, T Brinker… - Cerebrospinal fluid …, 2008 - Springer
This review integrates eight aspects of cerebrospinal fluid (CSF) circulatory dynamics:
formation rate, pressure, flow, volume, turnover rate, composition, recycling and …

Choroid plexus Aquaporins in CSF homeostasis and the Glymphatic system: their relevance for Alzheimer's disease

C Municio, L Carrero, D Antequera, E Carro - International Journal of …, 2023 - mdpi.com
The glymphatic system, a fluid-clearance pathway involved in brain waste clearance, is
known to be impaired in neurological disorders, including Alzheimer's disease (AD). For this …

Expression of the astrocyte water channel aquaporin-4 in the mouse brain

JA Hubbard, MS Hsu, MM Seldin, DK Binder - ASN neuro, 2015 - journals.sagepub.com
Aquaporin-4 (AQP4) is a bidirectional water channel that is found on astrocytes throughout
the central nervous system. Expression is particularly high around areas in contact with …

Regulation of brain aquaporins

M Zelenina - Neurochemistry international, 2010 - Elsevier
Three aquaporins are expressed in the brain. AQP4, the predominant brain water channel,
is expressed in astrocyte endfeet facing brain capillaries, perisynaptic spaces, and nodes of …

Water channel proteins (later called aquaporins) and relatives: past, present, and future

G Benga - IUBMB life, 2009 - Wiley Online Library
Water channels or water channel proteins (WCPs) are transmembrane proteins that have a
specific three‐dimensional structure with a pore that can be permeated by water molecules …

Distribution of sodium transporters and aquaporin-1 in the human choroid plexus

J Praetorius, S Nielsen - American Journal of Physiology …, 2006 - journals.physiology.org
The choroid plexus epithelium secretes electrolytes and fluid in the brain ventricular lumen
at high rates. Several channels and ion carriers have been identified as likely mediators of …

Aquaporin expression in the brains of patients with or without cerebral amyloid angiopathy

P Moftakhar, MD Lynch, JL Pomakian… - … of Neuropathology & …, 2010 - academic.oup.com
Aquaporins have recently been identified as protein channels involved in water transport.
These channels may play a role in the edema formation and alterations in microvascular …

The first discovered water channel protein, later called aquaporin 1: molecular characteristics, functions and medical implications

G Benga - Molecular aspects of medicine, 2012 - Elsevier
After a decade of work on the water permeability of red blood cells (RBC) Benga group in
Cluj-Napoca, Romania, discovered in 1985 the first water channel protein in the RBC …

Functional and transcriptional induction of aquaporin-1 gene by hypoxia; analysis of promoter and role of Hif-1α

I Abreu-Rodríguez, R Sánchez Silva, AP Martins… - PloS one, 2011 - journals.plos.org
Aquaporin-1 (AQP1) is a water channel that is highly expressed in tissues with rapid O2
transport. It has been reported that this protein contributes to gas permeation (CO2, NO and …