Prostate cancer (PCa) affects millions of men globally. Due to advances in understanding
genomic landscapes and biological functions, the treatment of PCa continues to improve …

Macrophages are crucial drivers of tumour-promoting inflammation. Tumour-associated
macrophages (TAMs) contribute to tumour progression at different levels: by promoting …

Strategies for management of patients with, or at risk for, medication-related osteonecrosis of
the jaw (MRONJ) were set forth in the American Association of Oral and Maxillofacial …

In this study, we investigated the mechanisms by which puerarin alleviates osteoclast-
related loss of bone mass in ovariectomy (OVX)-induced osteoporosis model mice. Puerarin …

The first full publications on the biological effects of the diphosphonates, later renamed
bisphosphonates, appeared in 1969, so it is timely after 40 years to review the history of their …

Local wound debridement in the diseased pulp space is the main step in root canal
treatment to prevent the tooth from being a source of infection. In this review article, the …

R-Aminophosphonic acids are broadly defined as analogues of amino acids in which the
carboxylic group is replaced by a phosphonic acid or related group (usually phosphonous or …

Hypercalcemia of malignancy is a common finding typically found in patients with advanced
stage cancers. We aimed to provide an updated review on the etiology, pathogenesis …

Bisphosphonates (BPs) are well established as the leading drugs for the treatment of
osteoporosis. There is new knowledge about how they work. The differences that exist …

Background Bone is the most common site of metastatic disease associated with breast
cancer (BC). Bisphosphonates inhibit osteoclast‐mediated bone resorption, and novel …