The complexity of many biological, social and technological systems stems from the richness
of the interactions among their units. Over the past decades, a variety of complex systems …

Coupled biological and chemical systems, neural networks, social interacting species, the
Internet and the World Wide Web, are only a few examples of systems composed by a large …

A key aim of postgenomic biomedical research is to systematically catalogue all molecules
and their interactions within a living cell. There is a clear need to understand how these …

Background Understanding the interaction among different species within a community and
their responses to environmental changes is a central goal in ecology. However, defining …

Praise for the first edition:… superb, beautifully written and organized work that takes an
engineering approach to systems biology. Alon provides nicely written appendices to …

The availability of large data sets has allowed researchers to uncover complex properties
such as large-scale fluctuations and heterogeneities in many networks, leading to the …

Transcription regulation networks control the expression of genes. The transcription
networks of well-studied microorganisms appear to be made up of a small set of recurring …

Recent research has revealed general principles in the structural and functional
organization of complex networks which are shared by various natural, social and …

Complex networks appear in almost every aspect of science and technology. Although most
results in the field have been obtained by analysing isolated networks, many real-world …

A celebrated and controversial hypothesis suggests that some biological systems—parts,
aspects, or groups of them—may extract important functional benefits from operating at the …