Recent trends in biocatalysis

D Yi, T Bayer, CPS Badenhorst, S Wu… - Chemical Society …, 2021 - pubs.rsc.org
Biocatalysis has undergone revolutionary progress in the past century. Benefited by the
integration of multidisciplinary technologies, natural enzymatic reactions are constantly …

A roadmap for metagenomic enzyme discovery

SL Robinson, J Piel, S Sunagawa - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to 2021 Metagenomics has yielded massive amounts of sequencing data
offering a glimpse into the biosynthetic potential of the uncultivated microbial majority. While …

[BUKU][B] Natural product biosynthesis: chemical logic and enzymatic machinery

CT Walsh, Y Tang - 2017 - books.google.com
Authored by leading experts in the enzymology of natural product biosynthesis, this textbook
provides a thorough description of the types of natural products, the biosynthetic pathways …

Molecular forecasting of domoic acid during a pervasive toxic diatom bloom

JK Brunson, M Thukral, JP Ryan, CR Anderson… - Proceedings of the …, 2024 - pnas.org
In 2015, the largest recorded harmful algal bloom (HAB) occurred in the Northeast Pacific,
causing nearly 100 million dollars in damages to fisheries and killing many protected marine …

Function and structure of a terpene synthase encoded in a giant virus genome

Y Jung, T Mitsuhashi, S Sato, M Senda… - Journal of the …, 2023 - ACS Publications
Giant viruses are nonstandard viruses with large particles and genomes. While previous
studies have shown that their genomes contain various sequences of interest, their genes …

Alternative metabolic pathways and strategies to high-titre terpenoid production in Escherichia coli

MA Rinaldi, CA Ferraz, NS Scrutton - Natural Product Reports, 2022 - pubs.rsc.org
Covering: up to 2021 Terpenoids are a diverse group of chemicals used in a wide range of
industries. Microbial terpenoid production has the potential to displace traditional …

[HTML][HTML] Toxicity of the Diatom Genus Pseudo-nitzschia (Bacillariophyceae): Insights from Toxicity Tests and Genetic Screening in the Northern Adriatic Sea

T Turk Dermastia, S Dall'Ara, J Dolenc, P Mozetič - Toxins, 2022 - mdpi.com
Diatoms of the genus Pseudo-nitzschia H. Peragallo are known to produce domoic acid
(DA), a toxin involved in amnesic shellfish poisoning (ASP). Strains of the same species are …

Domoic acid biosynthesis in the red alga Chondria armata suggests a complex evolutionary history for toxin production

TS Steele, JK Brunson, Y Maeno, R Terada… - Proceedings of the …, 2022 - pnas.org
Domoic acid (DA), the causative agent of amnesic shellfish poisoning, is produced by select
organisms within two distantly related algal clades: planktonic diatoms and red macroalgae …

Acquisition and evolution of the neurotoxin domoic acid biosynthesis gene cluster in Pseudo-nitzschia species

Z He, Q Xu, Y Chen, S Liu, H Song, H Wang… - Communications …, 2024 - nature.com
Of the hitherto over 60 taxonomically identified species in the genus of Pseudo-nitzschia, 26
have been confirmed to be toxigenic. Nevertheless, the acquisition and evolution of the toxin …

Biosynthesis of marine toxins

JR Chekan, TR Fallon, BS Moore - Current Opinion in Chemical Biology, 2020 - Elsevier
Throughout history, humans have encountered natural toxic chemicals from the ocean
environment, often through contaminated seafood. Although marine toxins can be harmful to …