Epstein–Barr virus-associated lymphomas

C Shannon-Lowe, AB Rickinson… - … Transactions of the …, 2017 - royalsocietypublishing.org
Epstein–Barr virus (EBV), originally discovered through its association with Burkitt
lymphoma, is now aetiologically linked to a remarkably wide range of lymphoproliferative …

Molecular mechanisms of EBV-driven cell cycle progression and oncogenesis

H Yin, J Qu, Q Peng, R Gan - Medical microbiology and immunology, 2019 - Springer
The early stage of oncogenesis is linked to the disorder of the cell cycle. Abnormal gene
expression often leads to cell cycle disorders, resulting in malignant transformation of …

Chromosomal fragile site breakage by EBV-encoded EBNA1 at clustered repeats

JSZ Li, A Abbasi, DH Kim, SM Lippman, LB Alexandrov… - Nature, 2023 - nature.com
Epstein–Barr virus (EBV) is an oncogenic herpesvirus associated with several cancers of
lymphocytic and epithelial origin,–. EBV encodes EBNA1, which binds to a cluster of 20 …

Epstein–Barr virus as a potentiator of autoimmune diseases

WH Robinson, S Younis, ZZ Love, L Steinman… - Nature Reviews …, 2024 - nature.com
Abstract The Epstein–Barr virus (EBV) is epidemiologically associated with development of
autoimmune diseases, including systemic lupus erythematosus, Sjögren syndrome …

[HTML][HTML] Translational genomics of nasopharyngeal cancer

CM Tsang, VWY Lui, JP Bruce, TJ Pugh… - Seminars in cancer biology, 2020 - Elsevier
Nasopharyngeal carcinoma (NPC), also named the Cantonese cancer, is a unique cancer
with strong etiological association with infection of the Epstein-Barr virus (EBV). With …

Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth

TE Messick, GR Smith, SS Soldan… - Science translational …, 2019 - science.org
Epstein-Barr virus (EBV) is a DNA tumor virus responsible for 1 to 2% of human cancers
including subtypes of Burkitt's lymphoma, Hodgkin's lymphoma, gastric carcinoma, and …

Control of viral latency by episome maintenance proteins

A De Leo, A Calderon, PM Lieberman - Trends in microbiology, 2020 - cell.com
The human DNA tumor viruses Epstein–Barr virus (EBV), Kaposi's sarcoma-associated
herpesvirus (KSHV), and human papillomavirus (HPV) share the common property of …

Epigenetic control of the Epstein-Barr lifecycle

R Guo, BE Gewurz - Current opinion in virology, 2022 - Elsevier
Epstein-Barr virus (EBV) infects 95% of adults worldwide, causes infectious mononucleosis,
is etiologically linked to multiple sclerosis and is associated with 200 000 cases of cancer …

The impact of Epstein-Barr virus infection on epigenetic regulation of host cell gene expression in epithelial and lymphocytic malignancies

MML Leong, ML Lung - Frontiers in Oncology, 2021 - frontiersin.org
Epstein-Barr virus (EBV) infection is associated with a variety of malignancies including
Burkitt's lymphoma (BL), Hodgkin's disease, T cell lymphoma, nasopharyngeal carcinoma …

[HTML][HTML] Epstein–Barr viruses: their immune evasion strategies and implications for autoimmune diseases

Y Zhao, Q Zhang, B Zhang, Y Dai, Y Gao, C Li… - International journal of …, 2024 - mdpi.com
Epstein–Barr virus (EBV), a member of the γ-herpesvirus family, is one of the most prevalent
and persistent human viruses, infecting up to 90% of the adult population globally. EBV's life …