Microglia are usually referred to as “the innate immune cells of the brain,”“the resident
macrophages of the central nervous system”(CNS), or “CNS parenchymal macrophages.” …

The continuous crosstalk between microglia and neurons is required for microglia
housekee** functions and contributes to brain homeostasis. Through these exchanges …

Microglia are highly motile glial cells that are proposed to mediate synaptic pruning during
neuronal circuit formation. Disruption of signaling between microglia and neurons leads to …

The molecular composition of presynaptic and postsynaptic neuronal terminals is dynamic,
and yet long-term stabilizations in postsynaptic responses are necessary for synaptic …

Synapse loss is an early feature shared by many neurodegenerative diseases, and it
represents the major correlate of cognitive impairment. Recent studies reveal that microglia …

Microglia are the primary immune cells of the central nervous system. However, recent data
indicate that microglia also contribute to diverse physiological and pathophysiological …

Microglia sense the changes in their environment. How microglia actively translate these
changes into suitable cues to adapt brain physiology is unknown. We reveal an activity …

Microglia are prominent immune cells in the central nervous system (CNS) and are critical
players in both neurological development and homeostasis, and in neurological diseases …

Investigations on the role of microglia in the brain have traditionally been focused on their
contributions to disease states. However, recent observations have now convincingly shown …

Microglia are the sentinels of the brain but a clear understanding of the factors that modulate
their activation in physiological and pathological conditions is still lacking. Here we …