Lubricants in pharmaceutical solid dosage forms

J Li, Y Wu - Lubricants, 2014 - mdpi.com
Lubrication plays a key role in successful manufacturing of pharmaceutical solid dosage
forms; lubricants are essential ingredients in robust formulations to achieve this. Although …

[SÁCH][B] Coupled DEM-CFD analyses of landslide-induced debris flows

T Zhao - 2017 - Springer
In recent years, the increasing impacts of landslide hazards on human lives and life-line
facilities worldwide has advanced the necessity to find out both economically acceptable …

An overview of pharmaceutical manufacturing for solid dosage forms

S Sacher, JG Khinast - Process simulation and data modeling in solid oral …, 2016 - Springer
In this chapter, the main processing steps and manufacturing aspects of solid dosage forms
are described and the relevant literature is reviewed. Starting with powder feeding, powder …

Investigation of landslide-induced debris flows by the DEM and CFD

T Zhao - 2014 - ora.ox.ac.uk
In recent years, the increasing impacts of landslide hazards on human lives and lifeline
facilities worldwide has advanced the necessity to find out both economically acceptable …

Numerical investigation into the influence of the punch shape on the mechanical behavior of pharmaceutical powders during compaction

A Krok, M Peciar, R Fekete - Particuology, 2014 - Elsevier
During the production of pharmaceutical tablets using powder compaction, certain common
problems can occur, such as sticking, tearing, cutting, and lamination. In the past, the …

Compaction of food powders: The influence of material properties and process parameters on product structure, strength, and dissolution

WR Mitchell, L Forny, T Althaus, D Dopfer… - Chemical Engineering …, 2017 - Elsevier
During pressure agglomeration of food powders, it is often difficult to control the final product
properties due to their complex material behaviours. The current study aims to better …

A systematic evaluation of poloxamers as tablet lubricants

J Dun, F Osei-Yeboah, P Boulas, Y Lin… - International journal of …, 2020 - Elsevier
Lubricants are important for both preserving the tooling of high-speed tablet presses and
attaining quality tablets. Magnesium stearate (MgSt) is most commonly used due to its …

Optimization of the process variables of roller compaction, on the basis of granules characteristics (flow, mechanical strength, and disintegration behavior): An …

A Khan - Drug Development and Industrial Pharmacy, 2019 - Taylor & Francis
The objective of the study was application of SeDeM-ODT expert system for optimization of
process variables for roller compaction and for the preparation of granules with better flow …

A drop penetration method to measure powder blend wettability

Y Wang, Z Liu, F Muzzio, G Drazer… - International journal of …, 2018 - Elsevier
Water wettability of pharmaceutical blends affects important quality attributes of final
products. We investigate the wetting properties of a pharmaceutical blend lubricated with …

Simplifying Johanson's roller compaction model to build a “Virtual Roller Compactor” as a predictive tool–Theory and practical application

C So, LY Leung, AR Muliadi, AS Narang… - International Journal of …, 2021 - Elsevier
The purpose of the study is to build a “virtual roller compactor” as a predictive tool to assess
the roll force (RF)-maximum pressure (P max) and RF-ribbon density relationship for …