Embryo-maternal signalling: how the embryo starts talking to its mother to accomplish implantation

A Herrler, U von Rango, HM Beier - Reproductive BioMedicine Online, 2003 - Elsevier
The process of implantation and trophoblast invasion is currently considered as the most
limiting factor for the establishment of pregnancy. Molecular interactions at the embryo …

Role of antisperm antibodies in infertility, pregnancy, and potential for contraceptive and antifertility vaccine designs: Research progress and pioneering vision

V AS, K Dhama, S Chakraborty, H Abdul Samad… - Vaccines, 2019 - mdpi.com
Sperm of humans, non-human primates, and other mammalian subjects is considered to be
antigenic. The effect of changes in autoimmunity on reproductive cells such as spermatozoa …

Phase I study utilizing a novel antigen-presenting cell–targeted vaccine with Toll-like receptor stimulation to induce immunity to self-antigens in cancer patients

MA Morse, R Chapman, J Powderly, K Blackwell… - Clinical Cancer …, 2011 - AACR
Purpose: The use of tumor-derived proteins as cancer vaccines is complicated by tolerance
to these self-antigens. Tolerance may be broken by immunization with activated, autologous …

Human chorionic gonadotropin as a pivotal endocrine immune regulator initiating and preserving fetal tolerance

A Schumacher - International journal of molecular sciences, 2017 - mdpi.com
The pregnancy hormone, human chorionic gonadotropin (hCG), is crucially involved in
processes such as implantation and placentation, two milestones of pregnancy whose …

Recent advances in contraceptive vaccine development: a mini-review

RK Naz, SK Gupta, JC Gupta, HK Vyas… - Human …, 2005 - academic.oup.com
Contraceptive vaccines (CV) may provide viable and valuable alternatives to the presently
available methods of contraception. The molecules that are being explored for CV …

The safety and immunogenicity of a CETP vaccine in healthy adults

MH Davidson, K Maki, D Umporowicz, A Wheeler… - Atherosclerosis, 2003 - Elsevier
A cholesterol ester transfer protein (CETP) vaccine (CETi-1) that induces auto-antibodies
that specifically bind and inhibit activity of endogenous CETP has been demonstrated in …

Endometrial receptivity: clinical assessment in relation to fertility, infertility, and antifertility

A Makker, MM Singh - Medicinal research reviews, 2006 - Wiley Online Library
Fertility in humans and other mammalian species depends absolutely on synchronous
events that render the develo** blastocyst and the receiving uterus competent for …

Infertility in mice induced by a recombinant ectromelia virus expressing mouse zona pellucida glycoprotein 3

RJ Jackson, DJ Maguire, LA Hinds… - Biology of …, 1998 - academic.oup.com
Population control has become a major problem in many wildlife species. Fertility control
through immunocontraception has been proposed as a method for reducing population size …

Unconventional actions of glycoprotein hormone subunits: A comprehensive review

B Querat - Frontiers in Endocrinology, 2021 - frontiersin.org
The glycoprotein hormones (GPH) are heterodimers composed of a common α subunit and
a specific β subunit. They act by activating specific leucine-rich repeat G protein-coupled …

The emerging role of immunoregulation of fibrinogen‐related procoagulant Fgl2 in the success or spontaneous abortion of early pregnancy in mice and humans

DA Clark, JW Ding, G Chaouat… - American Journal of …, 1999 - Wiley Online Library
PROBLEM: Abortion of chromosomally normal embryos in the CBA X DBA/2 mating
combination is triggered by release of Th1 cytokines (tumor necrosis factor [TNF]‐α …