The oral microbiota: dynamic communities and host interactions

RJ Lamont, H Koo, G Hajishengallis - Nature reviews microbiology, 2018‏ - nature.com
The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as
dental caries and periodontitis, two of the most prevalent microbially induced disorders …

Dental biofilm: ecological interactions in health and disease

PD Marsh, E Zaura - Journal of clinical periodontology, 2017‏ - Wiley Online Library
Background The oral microbiome is diverse and exists as multispecies microbial
communities on oral surfaces in structurally and functionally organized biofilms. Aim To …

Understanding dental caries as a non-communicable and behavioral disease: Management implications

RA Giacaman, CE Fernández… - Frontiers in oral …, 2022‏ - frontiersin.org
New paradigms in caries conceptualization have emerged during the last decades, leading
to intense debate and discussion on how to approach the disease, both from a preventive …

Streptococcus Sanguinis Biofilm Formation & Interaction with Oral Pathogens

B Zhu, LC Macleod, T Kitten, P Xu - Future microbiology, 2018‏ - Taylor & Francis
Caries and periodontitis are the two most common human dental diseases and are caused
by dysbiosis of oral flora. Although commensal microorganisms have been demonstrated to …

Association of polymicrobial interactions with dental caries development and prevention

Y Zhu, Y Wang, S Zhang, J Li, X Li, Y Ying… - Frontiers in …, 2023‏ - frontiersin.org
Dental caries is a common oral disease. In many cases, disruption of the ecological balance
of the oral cavity can result in the occurrence of dental caries. There are many cariogenic …

[HTML][HTML] Infective endocarditis: a focus on oral microbiota

C Del Giudice, E Vaia, D Liccardo, F Marzano… - Microorganisms, 2021‏ - mdpi.com
Infective endocarditis (IE) is an inflammatory disease usually caused by bacteria entering
the bloodstream and settling in the heart lining valves or blood vessels. Despite modern …

Social networking at the microbiome-host interface

RJ Lamont, G Hajishengallis, H Koo - Infection and Immunity, 2023‏ - journals.asm.org
Microbial species colonizing host ecosystems in health or disease rarely do so alone.
Organisms conglomerate into dynamic heterotypic communities or biofilms in which …

Fusobacterium nucleatum metabolically integrates commensals and pathogens in oral biofilms

A Sakanaka, M Kuboniwa, S Shimma, SA Alghamdi… - Msystems, 2022‏ - journals.asm.org
Fusobacterium nucleatum is a common constituent of the oral microbiota in both periodontal
health and disease. Previously, we discovered ornithine cross-feeding between F …

Sugars and beyond. The role of sugars and the other nutrients and their potential impact on caries

RA Giacaman - Oral Diseases, 2018‏ - Wiley Online Library
The traditional concept of caries as a multifactorial transmittable and infectious disease has
been challenged. Novel conceptual ideas have come to add to the complexity of this highly …

Live and let die: Hydrogen peroxide production by the commensal flora and its role in maintaining a symbiotic microbiome

S Redanz, X Cheng, RA Giacaman… - Molecular Oral …, 2018‏ - Wiley Online Library
The majority of commensal oral streptococci are able to generate hydrogen peroxide (H2O2)
during aerobic growth, which can diffuse through the cell membrane and inhibit competing …