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Traumatic brain injuries
Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe.
Mild TBI (the least severe form) is synonymous with concussion and is typically caused by …
Mild TBI (the least severe form) is synonymous with concussion and is typically caused by …
Plasma membrane integrity in health and disease: significance and therapeutic potential
Maintenance of plasma membrane integrity is essential for normal cell viability and function.
Thus, robust membrane repair mechanisms have evolved to counteract the eminent threat of …
Thus, robust membrane repair mechanisms have evolved to counteract the eminent threat of …
Myelin in Alzheimer's disease: culprit or bystander?
Alzheimer's disease (AD) is a neurodegenerative disorder with neuronal and synaptic
losses due to the accumulation of toxic amyloid β (Αβ) peptide oligomers, plaques, and …
losses due to the accumulation of toxic amyloid β (Αβ) peptide oligomers, plaques, and …
The contribution of β-amyloid, Tau and α-synuclein to blood–brain barrier damage in neurodegenerative disorders
Central nervous system (CNS) accumulation of fibrillary deposits made of Amyloid β (A β),
hyperphosphorylated Tau or α-synuclein (α-syn), present either alone or in the form of mixed …
hyperphosphorylated Tau or α-synuclein (α-syn), present either alone or in the form of mixed …
Chronic traumatic encephalopathy in athletes: progressive tauopathy after repetitive head injury
Since the 1920s, it has been known that the repetitive brain trauma associated with boxing
may produce a progressive neurological deterioration, originally termed dementia …
may produce a progressive neurological deterioration, originally termed dementia …
The molecular pathophysiology of concussive brain injury
Concussion (or mild traumatic brain injury, mTBI) is a biomechanically induced neurological
injury, resulting in an alteration of mental status, such as confusion or amnesia, which may …
injury, resulting in an alteration of mental status, such as confusion or amnesia, which may …
Traumatic brain injury and amyloid-β pathology: a link to Alzheimer's disease?
Traumatic brain injury (TBI) has devastating acute effects and in many cases seems to
initiate long-term neurodegeneration. Indeed, an epidemiological association between TBI …
initiate long-term neurodegeneration. Indeed, an epidemiological association between TBI …
The molecular pathophysiology of concussive brain injury–an update
Concussion (mild traumatic brain injury [TBI]), particularly with organized sports, has come to
the forefront of popular culture. Affecting about 1.6 million to 3.8 million athletes a year, its …
the forefront of popular culture. Affecting about 1.6 million to 3.8 million athletes a year, its …
Pathophysiology of cerebral ischemia and brain trauma: similarities and differences
Current knowledge regarding the pathophysiology of cerebral ischemia and brain trauma
indicates that similar mechanisms contribute to loss of cellular integrity and tissue …
indicates that similar mechanisms contribute to loss of cellular integrity and tissue …
Neuroprotective effects of curcumin
Neurodegenerative diseases result in the loss of functional neurons and synapses. Although
future stem cell therapies offer some hope, current treatments for most of these diseases are …
future stem cell therapies offer some hope, current treatments for most of these diseases are …