Real-time fluorescence imaging in intraoperative decision making for cancer surgery
Fluorescence-guided surgery is an intraoperative optical imaging method that provides
surgeons with real-time guidance for the delineation of tumours. Currently, in phase 1 and 2 …
surgeons with real-time guidance for the delineation of tumours. Currently, in phase 1 and 2 …
Fluorescence image-guided tumour surgery
Intraoperative fluorescent imaging can provide real-time identification of tumours, lymph
nodes, nerves and other healthy and malignant tissues during oncological surgery …
nodes, nerves and other healthy and malignant tissues during oncological surgery …
EGFR-targeted fluorescence molecular imaging for intraoperative margin assessment in oral cancer patients: a phase II trial
Inadequate surgical margins occur frequently in oral squamous cell carcinoma surgery.
Fluorescence molecular imaging (FMI) has been explored for intraoperative margin …
Fluorescence molecular imaging (FMI) has been explored for intraoperative margin …
Co-administered antibody improves penetration of antibody–dye conjugate into human cancers with implications for antibody–drug conjugates
Poor tissue penetration remains a major challenge for antibody-based therapeutics of solid
tumors, but proper dosing can improve the tissue penetration and thus therapeutic efficacy of …
tumors, but proper dosing can improve the tissue penetration and thus therapeutic efficacy of …
Targeted optical fluorescence imaging: a meta-narrative review and future perspectives
Purpose The aim of this review is to give an overview of the current status of targeted optical
fluorescence imaging in the field of oncology, cardiovascular, infectious and inflammatory …
fluorescence imaging in the field of oncology, cardiovascular, infectious and inflammatory …
[HTML][HTML] Fluorescence-guided imaging for resection margin evaluation in head and neck cancer patients using cetuximab-800CW: a quantitative dose-escalation study
Tumor-positive resection margins are present in up to 23% of head and neck cancer (HNC)
surgeries, as intraoperative techniques for real-time evaluation of the resection margins are …
surgeries, as intraoperative techniques for real-time evaluation of the resection margins are …
Optical molecular imaging can differentiate metastatic from benign lymph nodes in head and neck cancer
Identification of lymph node (LN) metastasis is essential for staging of solid tumors, and as a
result, surgeons focus on harvesting significant numbers of LNs during ablative procedures …
result, surgeons focus on harvesting significant numbers of LNs during ablative procedures …
Tumour-specific fluorescence-guided surgery for pancreatic cancer using panitumumab-IRDye800CW: a phase 1 single-centre, open-label, single-arm, dose …
Background Complete surgical resection remains the primary curative option for pancreatic
ductal adenocarcinoma, with positive margins in 30–70% of patients. In this study, we aimed …
ductal adenocarcinoma, with positive margins in 30–70% of patients. In this study, we aimed …
Improving oral cavity cancer diagnosis and treatment with fluorescence molecular imaging
Early diagnosis and radical surgical excision of oral squamous cell carcinomas are essential
for achieving optimal treatment outcomes. To date, diagnostic tools that rely on anatomical …
for achieving optimal treatment outcomes. To date, diagnostic tools that rely on anatomical …
Quicker, deeper and stronger imaging: A review of tumor-targeted, near-infrared fluorescent dyes for fluorescence guided surgery in the preclinical and clinical stages
J Jiao, J Zhang, F Yang, W Song, D Han, W Wen… - European Journal of …, 2020 - Elsevier
Cancer is a public health problem and the main cause of human mortality and morbidity
worldwide. Complete removal of tumors and metastatic lymph nodes in surgery is …
worldwide. Complete removal of tumors and metastatic lymph nodes in surgery is …