The Society for Immunotherapy in Cancer statement on best practices for multiplex immunohistochemistry (IHC) and immunofluorescence (IF) staining and validation

JM Taube, G Akturk, M Angelo… - Journal for …, 2020‏ - pmc.ncbi.nlm.nih.gov
Objectives The interaction between the immune system and tumor cells is an important
feature for the prognosis and treatment of cancer. Multiplex immunohistochemistry (mIHC) …

Epithelium segmentation using deep learning in H&E-stained prostate specimens with immunohistochemistry as reference standard

W Bulten, P Bándi, J Hoven, R Loo, J Lotz, N Weiss… - Scientific reports, 2019‏ - nature.com
Given the importance of gland morphology in grading prostate cancer (PCa), automatically
differentiating between epithelium and other tissues is an important prerequisite for the …

Two-stage selective ensemble of CNN via deep tree training for medical image classification

Y Yang, Y Hu, X Zhang, S Wang - IEEE transactions on …, 2021‏ - ieeexplore.ieee.org
Medical image classification is an important task in computer-aided diagnosis systems. Its
performance is critically determined by the descriptiveness and discriminative power of …

Toward computing cross-modality symmetric non-rigid medical image registration

S Mohanty, SP Dakua - IEEE Access, 2022‏ - ieeexplore.ieee.org
This paper describes a new non-rigid approach to register images from same-and cross-
imaging modalities such as magnetic resonance imaging, computed tomography, and 3D …

[HTML][HTML] RegWSI: Whole slide image registration using combined deep feature-and intensity-based methods: Winner of the ACROBAT 2023 challenge

M Wodzinski, N Marini, M Atzori, H Müller - Computer methods and …, 2024‏ - Elsevier
Background and objective The automatic registration of differently stained whole slide
images (WSIs) is crucial for improving diagnosis and prognosis by fusing complementary …

Unsupervised histological image registration using structural feature guided convolutional neural network

L Ge, X Wei, Y Hao, J Luo, Y Xu - IEEE Transactions on …, 2022‏ - ieeexplore.ieee.org
Registration of multiple stained images is a fundamental task in histological image analysis.
In supervised methods, obtaining ground-truth data with known correspondences is …

[HTML][HTML] A machine learning algorithm for simulating immunohistochemistry: development of SOX10 virtual IHC and evaluation on primarily melanocytic neoplasms

CR Jackson, A Sriharan, LJ Vaickus - Modern Pathology, 2020‏ - Elsevier
Immunohistochemistry (IHC) is a diagnostic technique used throughout pathology. A
machine learning algorithm that could predict individual cell immunophenotype based on …

[HTML][HTML] Whole slide image registration via multi-stained feature matching

MZ Hoque, A Keskinarkaus, P Nyberg, T Mattila… - Computers in Biology …, 2022‏ - Elsevier
In the recent decade, medical image registration and fusion process has emerged as an
effective application to follow up diseases and decide the necessary therapies based on the …

[HTML][HTML] Optimized tumour infiltrating lymphocyte assessment for triple negative breast cancer prognostics

MCA Balkenhol, F Ciompi, Ż Świderska-Chadaj… - The Breast, 2021‏ - Elsevier
The tumour microenvironment has been shown to be a valuable source of prognostic
information for different cancer types. This holds in particular for triple negative breast cancer …

FastNet: A lightweight convolutional neural network for tumors fast identification in mobile-computer-assisted devices

P **ao, Z Qin, D Chen, N Zhang, Y Ding… - IEEE Internet of …, 2023‏ - ieeexplore.ieee.org
Histopathology diagnosis is an important standard for breast tumors identifying. However,
histopathology image analysis is complex, tedious, and error-prone, due to the super …