Chemo-radiotherapy and systemic therapies have proven satisfactory outcomes as standard
treatments for various thoracic malignancies; however, adverse pulmonary effects, like …

Radiation-induced lung injury (RILI) encompasses any lung toxicity induced by radiation
therapy (RT) and manifests acutely as radiation pneumonitis and chronically as radiation …

Immunotherapy is radically changing the clinical management of patients affected by an
increasingly wide array of tumours. However, not all patients achieve long-term clinical …

The development of protective agents against harmful radiations has been a subject of
investigation for decades. However, effective (ideal) radioprotectors and radiomitigators …

Radiation-induced lung injury (RILI) is one of the most common and fatal complications of
thoracic radiotherapy, whereas no effective interventions are available. Andrographolide, an …

Lung, breast, and esophageal cancer represent three common malignancies with high
incidence and mortality worldwide. The management of these tumors critically relies on …

Aims: Radiotherapy is an effective treatment for thoracic malignancies, but it can cause
pulmonary injury and may lead to respiratory failure in a subset of patients. Extracellular …

Uncontrolled inflammation is responsible for acute and chronic diseases in the lung.
Regulating expression of pro-inflammatory genes in pulmonary tissue using small interfering …

Melatonin is a well‐known anti‐inflammatory and antioxidant molecule, which plays a
crucial role in various physiological functions. In this study, mice received a single dose of …

In recent decades, technical advances in surgery and radiotherapy, as well as
breakthroughs in the knowledge on cancer biology, have helped to substantially improve the …