Overview of the 2022 WHO classification of thyroid neoplasms

ZW Baloch, SL Asa, JA Barletta, RA Ghossein… - Endocrine …, 2022 - Springer
This review summarizes the changes in the 5th edition of the WHO Classification of
Endocrine and Neuroendocrine Tumors that relate to the thyroid gland. The new …

[HTML][HTML] Anaplastic thyroid carcinoma: an update

A Jannin, A Escande, A Al Ghuzlan, P Blanchard… - Cancers, 2022 - mdpi.com
Simple Summary Anaplastic thyroid carcinoma (ATC) has a dismal prognostic.
Chemotherapy and radiotherapy are the mainstem options for patients with ATC. In selected …

2021 American thyroid association guidelines for management of patients with anaplastic thyroid cancer: American thyroid association anaplastic thyroid cancer …

KC Bible, E Kebebew, J Brierley, JP Brito… - Thyroid, 2021 - liebertpub.com
Background: Anaplastic thyroid cancer (ATC) is a rare but highly lethal form of thyroid
cancer. Since the guidelines for the management of ATC by the American Thyroid …

Anaplastic transformation in thyroid cancer revealed by single-cell transcriptomics

L Lu, JR Wang, YC Henderson, S Bai, J Yang… - The Journal of clinical …, 2023 - jci.org
The deadliest anaplastic thyroid cancer (ATC) often transforms from indolent differentiated
thyroid cancer (DTC); however, the complex intratumor transformation process is poorly …

Efficacy and safety of larotrectinib in patients with TRK fusion-positive thyroid carcinoma

SG Waguespack, A Drilon, JJ Lin… - European journal of …, 2022 - academic.oup.com
Objective Larotrectinib is a highly selective tropomyosin receptor kinase (TRK) inhibitor with
demonstrated efficacy across various TRK fusion-positive solid tumours. We assessed the …

Molecular diagnostics in the evaluation of thyroid nodules: current use and prospective opportunities

J Patel, J Klopper, EE Cottrill - Frontiers in endocrinology, 2023 - frontiersin.org
Thyroid cancer is the most common endocrine malignancy with an estimated 43,800 new
cases to be diagnosed in 2022 and representing the 7th most common cancer in women …

The 2022 WHO classification of thyroid tumors: novel concepts in nomenclature and grading

CC Juhlin, O Mete, ZW Baloch - Endocrine-related cancer, 2023 - erc.bioscientifica.com
The 5th edition of the Classification of Endocrine and Neuroendocrine Tumors has been
released by the World Health Organization (WHO). This timely publication integrates several …

[HTML][HTML] PTEN dual lipid-and protein-phosphatase function in tumor progression

A Liu, Y Zhu, W Chen, G Merlino, Y Yu - Cancers, 2022 - mdpi.com
Simple Summary Phosphatase and tensin homolog deleted on chromosome ten (PTEN) is a
multifunctional tumor suppressor with protein-and lipid-phosphatase activities. The …

NTRK Fusion Genes in Thyroid Carcinomas: Clinicopathological Characteristics and Their Impacts on Prognosis

B Pekova, V Sykorova, K Mastnikova, E Vaclavikova… - Cancers, 2021 - mdpi.com
Simple Summary NTRK fusion genes are important but not well studied molecular markers
in thyroid cancer. Their identification could help improve diagnosis and prognosis, and …

Primary high‐grade non‐anaplastic thyroid carcinoma: a retrospective study of 364 cases

B Xu, J David, S Dogan, I Landa, N Katabi… - …, 2022 - Wiley Online Library
Aims We aimed to study the clinicopathological and molecular features of high‐grade non‐
anaplastic thyroid carcinomas (HGTCs), a carcinoma with a prognosis intermediate between …