The Hippo signaling pathway regulates diverse physiological processes, and its dysfunction
has been implicated in an increasing number of human diseases, including cancer. Here …

First discovered in Drosophila, the Hippo signaling pathway is a conserved regulator of
organ size. Central to this pathway is a kinase cascade leading from the tumor suppressor …

Neurons exhibit a limited ability of repair. Given that mechanical forces affect neuronal
outgrowth, it is important to investigate whether mechanosensitive ion channels may …

Type-specific dendrite morphology is a hallmark of the neuron and has important functional
implications in determining what signals a neuron receives and how these signals are …

Summary The Hippo (Hpo) kinase cascade restricts tissue growth by inactivating the
transcriptional coactivator Yorkie (Yki), which regulates the expression of target genes such …

The control of organ (or organism) size is a fundamental aspect of life that has long captured
human imagination. What makes an elephant grow a million times larger than a mouse …

Intense research over the past four years has led to the discovery and characterization of a
novel signalling network, known as the Salvador–Warts–Hippo (SWH) pathway, involved in …

The Hippo signaling pathway regulates organ size and tissue homeostasis from Drosophila
to mammals. Central to this pathway is a kinase cascade wherein Hippo (Hpo), in complex …

Abstract N 6-methyladenosine (m6A), the most prevalent internal modification on eukaryotic
mRNA, plays an essential role in various stress responses. The brain is uniquely vulnerable …

The “Hippo” signaling pathway has emerged as a major regulator of cell proliferation and
survival in metazoans. The pathway, as delineated by genetic and biochemical studies in …