Understanding the molecular mechanisms of the interplay between herbal medicines and gut microbiota

J Xu, HB Chen, SL Li - Medicinal research reviews, 2017 - Wiley Online Library
Herbal medicines (HMs) are much appreciated for their significant contribution to human
survival and reproduction by remedial and prophylactic management of diseases. Defining …

Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L

Q Gao, M Yang, Z Zuo - Acta Pharmacologica Sinica, 2018 - nature.com
Arctigenin (AR) and its glycoside, arctiin, are two major active ingredients of Arctium lappa L
(A lappa), a popular medicinal herb and health supplement frequently used in Asia. In the …

Progress in the treatment of drug-induced liver injury with natural products

Y Sun, Y Zhang, L **e, F Rong, X Zhu, J **e… - Pharmacological …, 2022 - Elsevier
There are numerous prescription drugs and non-prescription drugs that cause drug-induced
liver injury (DILI), which is the main cause of liver disease in humans around the globe. Its …

Natural compounds as safe therapeutic options for ulcerative colitis

M Gupta, V Mishra, M Gulati, B Kapoor, A Kaur… - …, 2022 - Springer
Ulcerative colitis (UC) is a chronic inflammatory bowel disease of unknown etiology. Several
conventional treatments for UC such as corticosteroids, immunosuppressive agents, tumor …

[HTML][HTML] Arctium lappa (Burdock): Insights from ethnopharmacology potential, chemical constituents, clinical studies, pharmacological utility and nanomedicine

N Yosri, SM Alsharif, J **ao, SG Musharraf… - Biomedicine & …, 2023 - Elsevier
Arctium lappa L. is a medicinal edible homologous plant, commonly known as burdock or
bardana, which belongs to the Asteraceae family. It is widely distributed throughout Northern …

Phytochemicals and inflammatory bowel disease: a review

I Hossen, W Hua, L Ting, A Mehmood… - Critical Reviews in …, 2022 - Taylor & Francis
Gastrointestinal tract is the second largest organ in the body that mainly functions in
nutrients and minerals intake through the intestinal barrier. Intestinal permeability maintains …

Targeting NF-κB pathway for treating ulcerative colitis: comprehensive regulatory characteristics of Chinese medicines

PD Lu, YH Zhao - Chinese medicine, 2020 - Springer
Nuclear factor-kappa B (NF-κB) is a kind of multi-functional nuclear transcription factor
involved in regulating gene transcription to influence pathological evolution of inflammatory …

Alpinetin attenuates inflammatory responses by suppressing TLR4 and NLRP3 signaling pathways in DSS-induced acute colitis

X He, Z Wei, J Wang, J Kou, W Liu, Y Fu, Z Yang - Scientific reports, 2016 - nature.com
Alpinetin, a composition of Alpinia katsumadai Hayata, has been reported to have a number
of biological properties, such as antibacterial, antitumor and other important therapeutic …

Development of ohmic-assisted green extraction technique with ultrasonic and microwave pretreatments: burdock (Arctium lappa L.) root extract

N Nikoomanesh, M Zandi, A Ganjloo - Chemical Engineering and …, 2024 - Elsevier
The present study was carried out to investigate and optimize the recovery of Burdock
(Arctium lappa L.) root extract (BRE) using Ohmic-assisted (OH) extraction method with …

Arctigenin: pharmacology, total synthesis, and progress in structure modification

D Wu, L **, X Huang, H Deng, Q Shen… - Journal of Enzyme …, 2022 - Taylor & Francis
Arctium lappa L. is a prevalent medicinal herb and a health supplement that is commonly
used in Asia. Over the last few decades, the bioactive component arctigenin has attracted …