Cysteinyl leukotriene receptor‐1 antagonists as modulators of innate immune cell function

AJ Theron, HC Steel, GR Tintinger… - Journal of …, 2014 - Wiley Online Library
Cysteinyl leukotrienes (cysLTs) are produced predominantly by cells of the innate immune
system, especially basophils, eosinophils, mast cells, and monocytes/macrophages …

Regulation of superoxide production in neutrophils: role of calcium influx

S Bréchard, EJ Tschirhart - Journal of Leucocyte Biology, 2008 - academic.oup.com
Upon stimulation, activation of NADPH oxidase complexes in neutrophils produces a burst
of superoxide anions contributing to oxidative stress and the development of inflammatory …

[HTML][HTML] Neutrophils kill antibody-opsonized cancer cells by trogoptosis

HL Matlung, L Babes, XW Zhao, M van Houdt… - Cell reports, 2018 - cell.com
Destruction of cancer cells by therapeutic antibodies occurs, at least in part, through
antibody-dependent cellular cytotoxicity (ADCC), and this can be mediated by various Fc …

Lonicerae japonicae flos attenuates neutrophilic inflammation by inhibiting oxidative stress

KH Lai, YL Chen, MF Lin, M El-Shazly, YC Chang… - Antioxidants, 2022 - mdpi.com
Lonicerae japonicae flos (LJ) is an Asian traditional herb that is used as a dietary
supplement, tea, and beverage to clear heat and quench thirst. However, no studies …

Neutrophil extracellular traps release induced by Leishmania: role of PI3Kγ, ERK, PI3Kσ, PKC, and [Ca2+]

T DeSouza-Vieira, A Guimarães-Costa… - Journal of Leucocyte …, 2016 - academic.oup.com
Upon in vitro stimulation, neutrophils undergo a cell death named netosis. This process is
characterized by extracellular release of chromatin scaffold associated with granular and …

[HTML][HTML] Pulmonary instillation of low doses of titanium dioxide nanoparticles in mice leads to particle retention and gene expression changes in the absence of …

M Husain, AT Saber, C Guo, NR Jacobsen… - Toxicology and applied …, 2013 - Elsevier
We investigated gene expression, protein synthesis, and particle retention in mouse lungs
following intratracheal instillation of varying doses of nano-sized titanium dioxide (nano …

Viscolin, a new chalcone from Viscum coloratum, inhibits human neutrophil superoxide anion and elastase release via a cAMP-dependent pathway

TL Hwang, YL Leu, SH Kao, MC Tang… - Free Radical Biology and …, 2006 - Elsevier
The mistletoe Viscum coloratum is used in traditional Chinese medicine to treat inflammatory
diseases. In this study, a cellular model in isolated human neutrophils, which are important …

Anti-inflammatory effects of the extract of indigo naturalis in human neutrophils

YK Lin, YL Leu, TH Huang, YH Wu, PJ Chung… - Journal of …, 2009 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Indigo naturalis is used by traditional Chinese
medicine to treat various inflammatory diseases. AIM OF THE STUDY: Topical indigo …

Regulation of glycolytic oscillations by mitochondrial and plasma membrane H+-ATPases

LF Olsen, AZ Andersen, A Lunding, JC Brasen… - Biophysical …, 2009 - cell.com
We investigated the coupling between glycolytic and mitochondrial membrane potential
oscillations in Saccharomyces cerevisiae under semianaerobic conditions. Glycolysis was …

A biomimetic membrane device that modulates the excessive inflammatory response to sepsis

F Ding, JH Song, JY Jung, L Lou, M Wang, L Charles… - PLoS …, 2011 - journals.plos.org
Objective Septic shock has a clinical mortality rate approaching fifty percent. The major
clinical manifestations of sepsis are due to the dysregulation of the host's response to …