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Childhood obesity, hypothalamic inflammation, and the onset of puberty: A narrative review
AM Tzounakou, G Stathori, G Paltoglou, G Valsamakis… - Nutrients, 2024 - mdpi.com
The onset of puberty, which is under the control of the hypothalamic–pituitary–gonadal
(HPG) axis, is influenced by various factors, including obesity, which has been associated …
(HPG) axis, is influenced by various factors, including obesity, which has been associated …
Sex as a determinant of age-related changes in the brain
DE Burmistrov, SV Gudkov, C Franceschi… - International Journal of …, 2024 - mdpi.com
The notion of notable anatomical, biochemical, and behavioral distinctions within male and
female brains has been a contentious topic of interest within the scientific community over …
female brains has been a contentious topic of interest within the scientific community over …
[HTML][HTML] Opposite changes in morphometric similarity of medial reward and lateral non-reward orbitofrontal cortex circuits in obesity
Obesity has a profound impact on metabolic health thereby adversely affecting brain
structure and function. However, the majority of previous studies used a single structural …
structure and function. However, the majority of previous studies used a single structural …
[HTML][HTML] Effect of bariatric surgery on cardio-psycho-metabolic outcomes in severe obesity: a randomized controlled trial
AC Koschker, B Warrings, C Morbach, F Seyfried… - Metabolism, 2023 - Elsevier
Objective Randomized evidence comparing the cardiovascular effects of surgical and
conservative weight management is lacking. Patients & methods In this single-center, open …
conservative weight management is lacking. Patients & methods In this single-center, open …
Bidirectional two-sample Mendelian randomization analyses support causal relationships between structural and diffusion imaging-derived phenotypes and the risk of …
Z Wang, X Yang, H Li, S Wang, Z Liu, Y Wang… - Translational …, 2024 - nature.com
Previous observational investigations suggest that structural and diffusion imaging-derived
phenotypes (IDPs) are associated with major neurodegenerative diseases; however …
phenotypes (IDPs) are associated with major neurodegenerative diseases; however …
The melanocortin‐4 receptor pathway and the emergence of precision medicine in obesity management
S Fansa, A Acosta - Diabetes, Obesity and Metabolism, 2024 - Wiley Online Library
Over the past few decades, there has been a global surge in the prevalence of obesity,
rendering it a globally recognized epidemic. Contrary to simply being a medical condition …
rendering it a globally recognized epidemic. Contrary to simply being a medical condition …
Network-targeted transcranial direct current stimulation of the hypothalamus appetite-control network: a feasibility study
The hypothalamus is the key regulator for energy homeostasis and is functionally connected
to striatal and cortical regions vital for the inhibitory control of appetite. Hence, the ability to …
to striatal and cortical regions vital for the inhibitory control of appetite. Hence, the ability to …
White adipose tissue distribution and amount are associated with increased white matter connectivity
L Okudzhava, S Schulz, E Fischi‐Gomez… - Human Brain …, 2024 - Wiley Online Library
Obesity represents a significant public health concern and is linked to various comorbidities
and cognitive impairments. Previous research indicates that elevated body mass index (BMI) …
and cognitive impairments. Previous research indicates that elevated body mass index (BMI) …
[HTML][HTML] Associations of Microbiota and Nutrition with Cognitive Impairment in Diseases
E Młynarska, P Jakubowska, W Frąk, A Gajewska… - Nutrients, 2024 - mdpi.com
Background/Objectives: Recent research highlights the growing interest in the impact of
nutrition on cognitive health and function in disease, as dietary habits are increasingly …
nutrition on cognitive health and function in disease, as dietary habits are increasingly …
Overweight during development dysregulates cellular metabolism and critical genes that control food intake in the prefrontal cortex
SC de Andrade Silva, MDT De Lemos… - Physiology & …, 2024 - Elsevier
Backgrounds and aims Childhood obesity is increasing substantially across the world. The
World Obesity Federation (WOF) and World Health Organization (WHO) predicted that in …
World Obesity Federation (WOF) and World Health Organization (WHO) predicted that in …