[HTML][HTML] Statistical methods for mediation analysis in the era of high-throughput genomics: current successes and future challenges
Mediation analysis investigates the intermediate mechanism through which an exposure
exerts its influence on the outcome of interest. Mediation analysis is becoming increasingly …
exerts its influence on the outcome of interest. Mediation analysis is becoming increasingly …
Structural and functional deficits and couplings in the cortico-striato-thalamo-cerebellar circuitry in social anxiety disorder
X Zhang, X Suo, X Yang, H Lai, N Pan, M He… - Translational …, 2022 - nature.com
Although functional and structural abnormalities in brain regions involved in the
neurobiology of fear and anxiety have been observed in patients with social anxiety disorder …
neurobiology of fear and anxiety have been observed in patients with social anxiety disorder …
Large-scale hypothesis testing for causal mediation effects with applications in genome-wide epigenetic studies
In genome-wide epigenetic studies, it is of great scientific interest to assess whether the
effect of an exposure on a clinical outcome is mediated through DNA methylations …
effect of an exposure on a clinical outcome is mediated through DNA methylations …
Estimating the natural indirect effect and the mediation proportion via the product method
Background The natural indirect effect (NIE) and mediation proportion (MP) are two
measures of primary interest in mediation analysis. The standard approach for mediation …
measures of primary interest in mediation analysis. The standard approach for mediation …
Dietary patterns and cardiometabolic risks in diverse less-developed ethnic minority regions: results from the China Multi-Ethnic Cohort (CMEC) Study
X **ao, Z Qin, X Lv, Y Dai, Z Ciren, Y Yangla… - The Lancet Regional …, 2021 - thelancet.com
Abstract Background In Western developed countries, food-based dietary patterns have
been associated with the risk of cardiometabolic diseases, but little is known about such …
been associated with the risk of cardiometabolic diseases, but little is known about such …
Causal mediation analysis using high‐dimensional image mediator bounded in irregular domain with an application to breast cancer
S Jiang, GA Colditz - Biometrics, 2023 - Wiley Online Library
Mammography is the primary breast cancer screening strategy. Recent methods have been
developed using the mammogram image to improve breast cancer risk prediction. However …
developed using the mammogram image to improve breast cancer risk prediction. However …
Suggested guidelines in reporting results from mediation analysis, standardized or unstandardized?
Mediation analysis is commonly implemented in psychological, epidemiological, and social
behavior studies to identify potential factors that mediate associations between exposures …
behavior studies to identify potential factors that mediate associations between exposures …
Parametric-regression–based causal mediation analysis of binary outcomes and binary mediators: moving beyond the rareness or commonness of the outcome
In the causal mediation framework, several parametric-regression–based approaches have
been introduced in the last decade for estimating natural direct and indirect effects. For a …
been introduced in the last decade for estimating natural direct and indirect effects. For a …
Exact parametric causal mediation analysis for a binary outcome with a binary mediator
With reference to causal mediation analysis, a parametric expression for natural direct and
indirect effects is derived for the setting of a binary outcome with a binary mediator, both …
indirect effects is derived for the setting of a binary outcome with a binary mediator, both …
An exact regression‐based approach for the estimation of natural direct and indirect effects with a binary outcome and a continuous mediator
In the causal mediation framework, a number of parametric regression‐based approaches
have been introduced in recent years for estimating natural direct and indirect effects for a …
have been introduced in recent years for estimating natural direct and indirect effects for a …