Gene-chips contain thousands of nucleotide sequences that allow simultaneous analysis of
the complex mixture of RNAs transcribed in cells. Like these gene-chips, major …

Type 1 diabetes is an autoimmune disease in which the insulin-producing pancreatic β cells
are destroyed at an early age by an immune process that involves both CD4 and CD8 T …

The existence of transplantation antigens, in addition to those encoded by genes in the
MHC, has been known for over half a century. The molecular identification of these …

Minor histocompatibility (H) Ags elicit T cell responses and thereby cause chronic graft
rejection and graft-vs-host disease among MHC identical individuals. Although numerous …

Major histocompatibility class I molecules display tens of thousands of peptides on the cell
surface for immune surveillance by T cells. The peptide repertoire represents virtually all …

We describe antagonist peptides that specifically inhibit cytolytic activity of T cell clones and
lines that express the antigen-specific receptor of CD8+ T lymphocyte clone 2C, which …

The products of minor histocompatibility (H) loci are serious barriers to tissue transplantation
even among major histocompatibility complex (MHC) identical individuals, frequently …

Using synthetic peptides, the HLA-B27-restricted CTL response to EBV in asymptomatic
virus carriers has been mapped to four epitope regions in EBV latent cycle Ags. One of these …

By analyzing T cell responses against foreign major histocompatibility complex (MHC)
molecules loaded with peptide libraries and defined self-and viral peptides, we demonstrate …

We studied the natural MHC class I display of measles virus (MV) epitopes. Peptide ligands
associated with HLA‐A* 0201 were purified from a B lymphoblastoid cell line prior to and …