Ever since the signal hypothesis was proposed in 1971, the exact nature of signal peptides
has been a focus point of research. The prediction of signal peptides and protein subcellular …

Aromatic compounds are ubiquitous in nature; they are the building blocks of abundant
lignin, and constitute a substantial proportion of synthetic chemicals and organic pollutants …

Abstract The MPI Bioinformatics Toolkit (https://toolkit. tuebingen. mpg. de) is a free, one-stop
web service for protein bioinformatic analysis. It currently offers 34 interconnected external …

Abstract The MPI Bioinformatics Toolkit (http://toolkit. tuebingen. mpg. de) is an open,
interactive web service for comprehensive and collaborative protein bioinformatic analysis. It …

Autotransport in Gram-negative bacteria denotes the ability of surface-localized proteins to
cross the outer membrane (OM) autonomously. Autotransporters perform this task with the …

Background In recent years, an exponential growing number of tools for protein sequence
analysis, editing and modeling tasks have been put at the disposal of the scientific …

Gram‐negative bacteria are surrounded by two membranes, called the outer and inner
membranes. The space between these membranes, the periplasm, is spanned by a …

Outer membrane proteins (OMPs) play important roles in cell biology. In addition, OMPs are
targeted by multiple drugs. The identification of OMPs from genomic sequences and …

Proteomics studies of pathogenic bacteria are an important basis for biomarker discovery
and for the development of antimicrobial drugs and vaccines. Especially where vaccines are …

Gram-negative bacteria and mitochondria are both covered by two distinct biological
membranes. These membrane systems have been maintained during the course of …