Behavioral sensitization to ethanol: Neural basis and factors that influence its acquisition and expression

R Camarini, RM Pautassi - Brain research bulletin, 2016 - Elsevier
Ethanol-induced behavioral sensitization (EBS) was first described in 1980, approximately
10 years after the phenomenon was described for psychostimulants. Ethanol acts on γ …

Assessing appetitive, aversive, and negative ethanol-mediated reinforcement through an immature rat model

RM Pautassi, ME Nizhnikov, NE Spear - Neuroscience & biobehavioral …, 2009 - Elsevier
The motivational effects of drugs play a key role during the transition from casual use to
abuse and dependence. Ethanol reinforcement has been successfully studied through …

Modulatory effects of Ampicillin/Sulbactam on glial glutamate transporters and metabotropic glutamate receptor 1 as well as reinstatement to cocaine-seeking …

AM Hammad, F Alasmari, YS Althobaiti… - Behavioural brain research, 2017 - Elsevier
Glutamatergic system has an important role in cocaine-seeking behavior. Studies have
reported that chronic exposure to cocaine induces downregulation of glutamate transporter …

Prenatal ethanol exposure increases ethanol intake and reduces c-Fos expression in infralimbic cortex of adolescent rats

MC Fabio, SM March, JC Molina, ME Nizhnikov… - Pharmacology …, 2013 - Elsevier
Prenatal ethanol exposure significantly increases later predisposition for alcohol intake, but
the mechanisms associated with this phenomenon remain hypothetical. This study analyzed …

Construction of vapor chambers used to expose mice to alcohol during the equivalent of all three trimesters of human development

RA Morton, MR Diaz, LA Topper… - Journal of visualized …, 2014 - pmc.ncbi.nlm.nih.gov
Exposure to alcohol during development can result in a constellation of morphological and
behavioral abnormalities that are collectively known as Fetal Alcohol Spectrum Disorders …

Prenatal alcohol exposure as a case of involuntary early onset of alcohol use: consequences and proposed mechanisms from animal studies

M Gaztañaga, A Angulo-Alcalde… - Frontiers in behavioral …, 2020 - frontiersin.org
Prenatal alcohol exposure has been found to be an important factor determining later
consumption of this drug. In humans, despite the considerable diversity of variables that …

Fetal exposure to moderate ethanol doses: heightened operant responsiveness elicited by ethanol‐related reinforcers

SM March, P Abate, NE Spear… - Alcoholism: Clinical and …, 2009 - Wiley Online Library
Background: Prenatal exposure to moderate ethanol doses during late gestation modifies
postnatal ethanol palatability and ingestion. The use of Pavlovian associative procedures …

Ethanol‐induced locomotor activity in adolescent rats and the relationship with ethanol‐induced conditioned place preference and conditioned taste aversion

MB Acevedo, ME Nizhnikov, NE Spear… - Developmental …, 2013 - Wiley Online Library
Adolescent rats exhibit ethanol‐induced locomotor activity (LMA), which is considered an
index of ethanol's motivational properties likely to predict ethanol self‐administration, but few …

Opioid antagonists block the acquisition of ethanol-mediated conditioned tactile preference in infant rats

ME Nizhnikov, RM Pautassi, E Truxell, NE Spear - Alcohol, 2009 - Elsevier
It has been difficult to find conditioned preference for tactile cues paired with ethanol
intoxication in rats. Toward understanding the ontogeny of ethanol reinforcement, we aimed …

High ethanol dose during early adolescence induces locomotor activation and increases subsequent ethanol intake during late adolescence

MB Acevedo, JC Molina, ME Nizhnikov… - Developmental …, 2010 - Wiley Online Library
Adolescent initiation of ethanol consumption is associated with subsequent heightened
probability of ethanol use disorders. The present study examined the relationship between …