Roles of macrophage polarization and macrophage-derived miRNAs in pulmonary fibrosis
A Kishore, M Petrek - Frontiers in immunology, 2021 - frontiersin.org
This mini-review summarizes the current evidence for the role of macrophage activation and
polarization in inflammation and immune response pertinent to interstitial lung disease …
polarization in inflammation and immune response pertinent to interstitial lung disease …
PLGA-based micro/nanoparticles: an overview of their applications in respiratory diseases
X Guo, X Zuo, Z Zhou, Y Gu, H Zheng, X Wang… - International Journal of …, 2023 - mdpi.com
Respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD),
are critical areas of medical research, as millions of people are affected worldwide. In fact …
are critical areas of medical research, as millions of people are affected worldwide. In fact …
Application of micro RNA s in diagnosis and treatment of cardiovascular disease
A Wronska, I Kurkowska‐Jastrzebska… - Acta …, 2015 - Wiley Online Library
Cardiovascular disease (CVD) is a major cause of morbidity and mortality worldwide.
Innovative, more stringent diagnostic and prognostic biomarkers and effective treatment …
Innovative, more stringent diagnostic and prognostic biomarkers and effective treatment …
Cytokine storm in the pathophysiology of COVID-19: Possible functional disturbances of miRNAs
Abstract SARS-CoV-2, as the causative agent of COVID-19, is an enveloped positives-sense
single-stranded RNA virus that belongs to the Beta-CoVs sub-family. A sophisticated hyper …
single-stranded RNA virus that belongs to the Beta-CoVs sub-family. A sophisticated hyper …
Pulmonary delivery of Nanocomposite Microparticles (NCMPs) incorporating miR-146a for treatment of COPD
The treatment and management of COPD by inhalation to the lungs has emerged as an
attractive alternative route to oral dosing due to higher concentrations of the drug being …
attractive alternative route to oral dosing due to higher concentrations of the drug being …
MicroRNAs in inflammatory heart diseases and sepsis-induced cardiac dysfunction: a potential scope for the future?
M Mirna, V Paar, R Rezar, A Topf, M Eber, UC Hoppe… - Cells, 2019 - mdpi.com
Background: MicroRNAs (miRNAs) are small, single-stranded RNA sequences that regulate
gene expression on a post-transcriptional level. In the last few decades, various trials have …
gene expression on a post-transcriptional level. In the last few decades, various trials have …
Regenerative cardiovascular therapies: stem cells and beyond
B Wernly, M Mirna, R Rezar, C Prodinger… - International journal of …, 2019 - mdpi.com
Although reperfusion therapy has improved outcomes, acute myocardial infarction (AMI) is
still associated with both significant mortality and morbidity. Once irreversible myocardial cell …
still associated with both significant mortality and morbidity. Once irreversible myocardial cell …
MicroRNAs: Key modulators of inflammation-associated diseases
Inflammation is a multifaceted biological and pathophysiological response to injuries,
infections, toxins, and inflammatory mechanisms that plays a central role in the progression …
infections, toxins, and inflammatory mechanisms that plays a central role in the progression …
Targeting COPD with PLGA‐Based Nanoparticles: Current Status and Prospects
J Saxena, M Bisen, A Misra… - BioMed Research …, 2022 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is pulmonary emphysema characterized by
blockage in the airflow resulting in the long‐term breathing problem, hence a major cause of …
blockage in the airflow resulting in the long‐term breathing problem, hence a major cause of …
Polymeric nanoparticles for the delivery of miRNA to treat Chronic Obstructive Pulmonary Disease (COPD)
RNA interference (RNAi) based therapeutics are considered an endogenous mechanism for
modulating gene expression. In addition, microRNAs (miRNAs) may be tractable targets for …
modulating gene expression. In addition, microRNAs (miRNAs) may be tractable targets for …