Kaposi sarcoma

E Cesarman, B Damania, SE Krown, J Martin… - Nature reviews Disease …, 2019‏ - nature.com
Kaposi sarcoma (KS) gained public attention as an AIDS-defining malignancy; its
appearance on the skin was a highly stigmatizing sign of HIV infection during the height of …

Molecular mechanisms of viral oncogenesis in humans

NA Krump, J You - Nature Reviews Microbiology, 2018‏ - nature.com
Viral infection is a major contributor to the global cancer burden. Recent advances have
revealed that seven known oncogenic viruses promote tumorigenesis through shared host …

Kaposi's sarcoma and its associated herpesvirus

EA Mesri, E Cesarman, C Boshoff - Nature Reviews Cancer, 2010‏ - nature.com
Kaposi's sarcoma (KS) is the most common cancer in HIV-infected untreated individuals.
Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8 …

Kaposi sarcoma herpesvirus-associated cancers and related diseases

PH Goncalves, J Ziegelbauer, TS Uldrick… - Current Opinion in …, 2017‏ - journals.lww.com
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[HTML][HTML] Broad action of Hsp90 as a host chaperone required for viral replication

R Geller, S Taguwa, J Frydman - … et Biophysica Acta (BBA)-Molecular Cell …, 2012‏ - Elsevier
Viruses are intracellular pathogens responsible for a vast number of human diseases. Due
to their small genome size, viruses rely primarily on the biosynthetic apparatus of the host for …

Gammaherpesviruses and lymphoproliferative disorders

E Cesarman - Annual Review of Pathology: Mechanisms of …, 2014‏ - annualreviews.org
Epstein–Barr virus (EBV) and Kaposi's sarcoma herpesvirus (KSHV), formally designated
human herpesvirus 4 (HHV-4) and 8 (HHV-8), respectively, are viruses that can cause a …

ITAM-mediated tonic signalling through pre-BCR and BCR complexes

JG Monroe - Nature Reviews Immunology, 2006‏ - nature.com
Studies carried out over the past few years provide strong support for the idea that Igα–Igβ-
containing complexes such as the pre-B-cell receptor and the B-cell receptor can signal …

Integrin αvβ3 is a coreceptor for human cytomegalovirus

X Wang, DY Huang, SM Huong, ES Huang - Nature medicine, 2005‏ - nature.com
Human cytomegalovirus (HCMV) is a widespread opportunistic pathogen that causes birth
defects in newborns and severe disease in immunocompromised individuals. The broad …

The role of gammaherpesviruses in cancer pathogenesis

HC Jha, S Banerjee, ES Robertson - Pathogens, 2016‏ - mdpi.com
Worldwide, one fifth of cancers in the population are associated with viral infections. Among
them, gammaherpesvirus, specifically HHV4 (EBV) and HHV8 (KSHV), are two oncogenic …

Kaposi sarcoma-associated herpesvirus (KSHV): molecular biology and oncogenesis

KW Wen, B Damania - Cancer letters, 2010‏ - Elsevier
Kaposi sarcoma-associated herpesvirus (KSHV) is a double-stranded DNA herpesvirus
belonging to the γ-herpesvirinae subfamily. KSHV has been associated with the …