Targeting protein-protein interactions (PPIs) has been recently recognized as an emerging
therapeutic approach for several diseases. Up today, more than half a million PPI …

Co-fractionation/mass spectrometry (CF/MS) enables the map** of endogenous
macromolecular networks on a proteome scale, but current methods are experimentally …

Biological systems respond to perturbations through the rewiring of molecular interactions,
organised in gene regulatory networks (GRNs). Among these, the increasingly high …

A global protein interactome ensures the maintenance of regulatory, signaling and structural
processes in cells, but at the same time, aberrations in the repertoire of protein–protein …

The identification of biomolecules associated with papillary thyroid cancer (PTC) has upmost
importance for the elucidation of the disease mechanism and the development of effective …

Space particle radiation is a major environmental factor in spaceflight, and it is known to
cause body damage and even trigger cancer, but with unknown molecular etiologies. To …

Simple Summary In its early stages, colorectal cancer (CRC) is a localized tumor, but when it
metastasizes, it has dramatic consequences. Murine models in CRC research are important …

Breast cancer is the second leading cause of death for women in the United States, and
early detection could offer patients the opportunity to receive early intervention. The current …

Breast cancer is an individually unique, multi-faceted and chameleonic disease, an eternal
challenge for the new era of high-integrated precision diagnostic and personalized …

Most methods for explaining black-box classifiers (eg, on tabular data, images, or time
series) rely on measuring the impact that removing/perturbing features has on the model …