The element selenium was discovered in 1818 by the Swedish chemist Berzelius and was
named after the Greek goddess of the moon, Selene. 1 In biology, selenium was long …

Epidemiological studies, preclinical investigations and clinical intervention trials support the
role of selenium compounds as potent cancer chemopreventive agents; the dose and the …

Transient receptor potential (TRP) channels modulate calcium levels in eukaryotic cells in
response to external signals. A novel transient receptor potential channel has the ability to …

Selenium is an essential trace element. It is, however toxic at concentration little above
which is required for health. Selenium is incorporated into proteins as selenocysteine, the …

Selenium represents an essential element for organisms as various diseases can result from
selenium deficiency. As a consequence, selenium-containing heterocycles are of …

Eukaryotic elongation factor 2 kinase (eEF2K) is an unusual protein kinase that regulates
the elongation stage of protein synthesis by phosphorylating and inhibiting its only known …

Eukaryotic elongation factor-2 kinase (eEF2K) relays growth and stress signals to protein
synthesis through phosphorylation and inactivation of eukaryotic elongation factor 2 (eEF2) …

Recently many syntheses of compounds containing selenium have been studied and
reported because of the interesting reactivities1 and their potential pharmaceutical …

Recent evidence suggests that the machinery of protein synthesis may provide novel targets
for anticancer drugs. For example, aberrations in protein synthesis are commonly …

Eukaryotic elongation factor-2 kinase (eEF2K), an atypical member of alpha-kinase family, is
highly overexpressed in breast, pancreatic, brain, and lung cancers, and associated with …