Fluorescence-guided surgery

T Nagaya, YA Nakamura, PL Choyke… - Frontiers in …, 2017 - frontiersin.org
Surgical resection of cancer remains an important treatment modality. Despite advances in
preoperative imaging, surgery itself is primarily guided by the surgeon's ability to locate …

Current and future strategies for treatment of glioma

NAO Bush, SM Chang, MS Berger - Neurosurgical review, 2017 - Springer
Gliomas are one of the most common types of primary brain tumors and have remained
particularly challenging to treat. This review illustrates a multidisciplinary approach to the …

Diagnosis, removal, or mechanical damaging of tumor using plasmonic nanobubbles

DO Lapotko, K Hleb - US Patent 10,471,159, 2019 - Google Patents
Processes of intraoperative diagnosis and elimination of tumors or micro-tumors or cancer
cells or tumor micro environment (TME) with plasmonic nanobubbles (PNBS) are disclosed …

Nanotechnology strategies to advance outcomes in clinical cancer care

CM Hartshorn, MS Bradbury, GM Lanza, AE Nel… - ACS …, 2018 - ACS Publications
Ongoing research into the application of nanotechnology for cancer treatment and diagnosis
has demonstrated its advantages within contemporary oncology as well as its intrinsic …

Tumor-specific uptake of fluorescent bevacizumab–IRDye800CW microdosing in patients with primary breast cancer: a phase I feasibility study

LE Lamberts, M Koch, JS de Jong… - Clinical Cancer …, 2017 - aacrjournals.org
Purpose: To provide proof of principle of safety, breast tumor–specific uptake, and positive
tumor margin assessment of the systemically administered near-infrared fluorescent tracer …

Illuminating the future of precision cancer surgery with fluorescence imaging and artificial intelligence convergence

H Cheng, H Xu, B Peng, X Huang, Y Hu… - NPJ Precision …, 2024 - nature.com
Real-time and accurate guidance for tumor resection has long been anticipated by
surgeons. In the past decade, the flourishing material science has made impressive …

Intraoperative imaging in pathology-assisted surgery

FJ Voskuil, J Vonk, B van der Vegt, S Kruijff… - Nature biomedical …, 2022 - nature.com
The pathological assessment of surgical specimens during surgery can reduce the
incidence of positive resection margins, which otherwise can result in additional surgeries or …

Randomized clinical trial of intraoperative parathyroid gland angiography with indocyanine green fluorescence predicting parathyroid function after thyroid surgery

J Vidal Fortuny, SM Sadowski, V Belfontali… - Journal of British …, 2018 - academic.oup.com
Background Hypoparathyroidism, the most common complication after thyroid surgery, leads
to hypocalcaemia and significant medical problems. An RCT was undertaken to determine …

Near-infrared fluorescence imaging in immunotherapy

Y Ji, C Jones, Y Baek, GK Park, S Kashiwagi… - Advanced drug delivery …, 2020 - Elsevier
Near-infrared (NIR) light possesses many suitable optophysical properties for medical
imaging including low autofluorescence, deep tissue penetration, and minimal light …

Molecular fluorescence-guided surgery of peritoneal carcinomatosis of colorectal origin: a single-centre feasibility study

NJ Harlaar, M Koller, SJ de Jongh… - The Lancet …, 2016 - thelancet.com
Background Optimum cytoreductive surgery combined with hyperthermic intraperitoneal
chemotherapy (HIPEC) is essential for the curative treatment of peritoneal carcinomatosis of …