Superparamagnetic iron oxide nanoparticles (SPION) with appropriate surface chemistry
have been widely used experimentally for numerous in vivo applications such as magnetic …

The microenvironment within tumors is significantly different from that in normal tissues. A
major difference is seen in the chaotic vasculature of tumors, which results in unbalanced …

Background: A surrogate marker for treatment response that can be observed earlier than
comparison of sequential magnetic resonance imaging (MRI) scans, which depends on …

Objective To perform a meta-analysis exploring the correlation between the apparent
diffusion coefficient (ADC) and tumor cellularity in patients. Materials and Methods We …

Assessment of radiation and chemotherapy efficacy for brain cancer patients is traditionally
accomplished by measuring changes in tumor size several months after therapy has been …

An imaging biomarker that would provide for an early quantitative metric of clinical treatment
response in cancer patients would provide for a paradigm shift in cancer care. Currently …

Purpose: The aim of this study was to investigate the utility of apparent diffusion coefficient
(ADC) for prediction and early detection of treatment response in head and neck squamous …

The aim of this study was to investigate whether apparent diffusion coefficients (ADCs) could
be used as measures of cell density and necrotic fraction of tumors. Tumors of four human …

The C2 domain of synaptotagmin I, which binds to anionic phospholipids in cell membranes,
was shown to bind to the plasma membrane of apoptotic cells by both flow cytometry and …

Purpose To determine whether changes in apparent diffusion coefficients (ADCs) of rectal
carcinoma obtained 1 week after the beginning of chemotherapy and radiation therapy …