[HTML][HTML] An Azomethine Derivative, BCS3, Targets XIAP and cIAP1/2 to Arrest Breast Cancer Progression Through MDM2-p53 and Bcl-2-Caspase Signaling …
Background: Breast cancer influences more than 2 million women worldwide annually.
Since apoptotic dysregulation is a cancer hallmark, targeting apoptotic regulators …
Since apoptotic dysregulation is a cancer hallmark, targeting apoptotic regulators …
Identification of Genes Crucial for Biological Processes in Breast Cancer Liver Metastasis Relapse
T Kwok, S Yeguvapalli, KN Chitrala - International Journal of Molecular …, 2024 - mdpi.com
Breast cancer, when advancing to a metastatic stage, involves the liver, impacting over 50%
of cases and significantly diminishing survival rates. Presently, a lack of tailored therapeutic …
of cases and significantly diminishing survival rates. Presently, a lack of tailored therapeutic …
[HTML][HTML] Serum CD133-Associated Proteins Identified by Machine Learning Are Connected to Neural Development, Cancer Pathways, and 12-Month Survival in …
T Joyce, E Tasci, S Jagasia, J Shephard, S Chappidi… - Cancers, 2024 - mdpi.com
Simple Summary Glioblastoma (GBM) is an aggressive form of brain cancer characterized
by its poor prognosis due to its resistance and recurrence capabilities. Liquid biopsies have …
by its poor prognosis due to its resistance and recurrence capabilities. Liquid biopsies have …
[HTML][HTML] Activity-Regulated Cytoskeleton-Associated Protein Gene Expression Is Associated With High Infiltration of Stromal Cells and Immune Cells, but With Less …
Background Peritumoral lidocaine infiltration prior to excision is associated with better
survival in breast cancer (BC), which led us to hypothesize that innervation to the tumor …
survival in breast cancer (BC), which led us to hypothesize that innervation to the tumor …
Apo10 and TKTL1 in blood macrophages as potential biomarkers for early diagnosis of operable breast cancer
M Wu, Q Huang, L Zhang, Y Liu, M Zeng… - Breast Cancer Research …, 2024 - Springer
Objective Blood macrophage Apo10 and TKTL1 detection is a novel, noninvasive cancer
screening approach, but its relevance in breast cancer remains uncertain. We compared the …
screening approach, but its relevance in breast cancer remains uncertain. We compared the …
Comparative transcriptomic and metabolomic analysis of FTO knockout and wild-type porcine iliac artery endothelial cells
L **e, N Fan, X Ding, T Zhang, W Wang, P Ji, H Wu - Gene, 2025 - Elsevier
The fat mass and obesity associated (FTO) gene, previously identified as a pivotal genetic
locus associated with adiposity, has recently been linked to various cancers. In this study …
locus associated with adiposity, has recently been linked to various cancers. In this study …
Potential Role of AKR1B1 Gene Methylation in Diagnosis of Patients With Breast Cancer
M El-Far, MA Abdelrazek, BM Foda… - Clinical Medicine …, 2024 - journals.sagepub.com
Background: In addition to the great challenge of early diagnosis and prognosis in breast
cancer (BC), the role of gene promoters in BC remains largely unexplored. This study aimed …
cancer (BC), the role of gene promoters in BC remains largely unexplored. This study aimed …
In Silico Discovery of Multi-Target Natural Ligands and Efficient siRNA Design for Overcoming Drug Resistance in Breast Cancer via Local Therapy
In this study, we designed an efficient siRNA for PKMYT1 gene knockdown, and evaluated
the binding affinities of different natural ligands to crucial proteins involved in breast cancer …
the binding affinities of different natural ligands to crucial proteins involved in breast cancer …
Role of Molecular-Genetic Profiling and Artificial Intelligence in Breast Cancer Diagnosis and insight into Targeted Pharmacotherapeutics
S Umakanthan - London Journal of Medical and Health Research, 2024 - journalspress.uk
Breast cancer is a complex and diverse disease with varying responses to therapeutics. To
address this diversity and offer personalized treatment plans, molecular and genetic …
address this diversity and offer personalized treatment plans, molecular and genetic …
EPYC promotes laryngeal cancer carcinogenesis and angiogenesis via theWnt-Axin-β-catenin/VEGFR1 pathway
D Zhou, F Liu, X Li, F Lv - 2024 - researchsquare.com
Background EPYC is a member of a small family of leucine-rich repetitive proteoglycans
(SLRPs) and contributes to the carcinogenesis of different cancers. However, the role of …
(SLRPs) and contributes to the carcinogenesis of different cancers. However, the role of …