Monoclonal antibodies (mAbs) are often selected from antigen-specific single B cells
derived from different hosts, which are notably short-lived in ex vivo culture conditions and …

Droplet microfluidic technology has revolutionized biomolecular analytical research, as it
has the capability to reserve the genotype-to-phenotype linkage and assist for revealing the …

Monoclonal antibodies are increasingly used to prevent and treat viral infections and are
pivotal in pandemic response efforts. Antibody-secreting cells (ASCs; plasma cells and …

A microfluidic-based surface-enhanced Raman scattering (SERS) platform for analyzing
cytokines secreted by single cells is reported based on the elaborate bioconjugation of the …

Antibody discovery is bottlenecked by the individual expression and evaluation of antigen-
specific hits. Here, we address this bottleneck by develo** a workflow combining cell-free …

Droplet microfluidics has revolutionized the biomedical and drug development fields by
allowing for independent microenvironments to conduct drug screening at the single cell …

High-throughput screening and enrichment of antibody-producing cells have many
important applications. Herein, we present a droplet microfluidic approach for high …

Single-cell proteomics (SCP) reveals phenotypic heterogeneity by profiling individual cells,
their biological states and functional outcomes upon signaling activation that can hardly be …

Antibody-secreting cells (ASC), plasmablasts and plasma cells, are terminally differentiated
B cells responsible for large-scale production and secretion of antibodies. ASC are derived …

Specific antibodies are widely used in the biomedical field. Current screening methods for
specific antibodies mainly involve hybridoma technology and antibody engineering …