Integrated continuous pharmaceutical technologies—a review

A Domokos, B Nagy, B Szilagyi, G Marosi… - … Process Research & …, 2021 - ACS Publications
Innovation in the pharmaceutical industry has been limited for a long time to the research
and development of new active compounds; meanwhile, the structure of the production …

Status of Industry 4.0 applications in healthcare 4.0 and Pharma 4.0

HM Inuwa, AR Raja, A Kumar, B Singh… - Materials Today …, 2022 - Elsevier
Industry 4.0 enabling technologies form the building foundation through which industrial
automation having intelligent systems can become possible in the 21 st century. By …

[HTML][HTML] Digital UV/VIS imaging: a rapid PAT tool for crushing strength, drug content and particle size distribution determination in tablets

LA Mészáros, DL Galata, L Madarász, Á Köte… - International Journal of …, 2020 - Elsevier
Abstract The Process Analytical Technology (PAT) and the Quality-by-Design (QbD)
approaches can efficiently facilitate the shift to the desired continuous manufacturing and …

Corona alternating current electrospinning: A combined approach for increasing the productivity of electrospinning

B Farkas, A Balogh, R Cselkó, K Molnár… - International journal of …, 2019 - Elsevier
Corona alternating current electrospinning (C-ACES), a scaled-up productivity
electrospinning method was developed by combining the intense forces of the alternating …

Continuous manufacturing of orally dissolving webs containing a poorly soluble drug via electrospinning

A Domokos, A Balogh, D Dénes, G Nyerges… - European Journal of …, 2019 - Elsevier
An orally dissolving web (ODW) formulation of poorly soluble carvedilol (CAR) was
developed and manufactured continuously using electrospinning (ES) as a key technology …

[HTML][HTML] The effect of manufacturing technologies on the flame retardancy of carbon fibre reinforced epoxy resin composites

A Toldy, Á Pomázi, B Szolnoki - Polymer Degradation and Stability, 2020 - Elsevier
We prepared reference and flame-retarded carbon fibre reinforced composites both by liquid
composite moulding, in particular vacuum infusion, and by hand lamination followed by hot …

Development of intumescent flame retardant for polypropylene: Bio-epoxy resin microencapsulated ammonium-polyphosphate

TTN Thanh, KE Decsov, K Bocz, G Marosi… - Periodica Polytechnica …, 2022 - pp.bme.hu
As polypropylene (PP) has no charring ability on its own due to the lack of hydroxyl
functional groups, the flame retardant system needs the addition of carbonizing agent in a …

The Effect of Surfactants and pH Modifying Agents on the Dissolution and Permeation of Pimobendan

P Tőzsér, LL Kovács, S Kádár, D Csicsák… - Periodica Polytechnica …, 2023 - pp.bme.hu
Solubility and permeability are key parameters for establishing in vitro-in vivo correlation for
poorly water-soluble active pharmaceutical ingredients (APIs). Recent studies demonstrate …

Preparation and Characterization of Microencapsulated Ammonium Polyphosphate with Polyurethane Shell and Its Flame Retardance in Polypropylene

TT Nguyen Thanh, Z Yusifov, B Tóth, K Bocz, P Márton… - Fire, 2024 - mdpi.com
Polypropylene (PP) shows no charring ability in burning due to the lack of hydroxyl
functional groups; thus, the flame retardant system needs an additional amount of …

[PDF][PDF] Development of integrated continuous pharmaceutical technologies

A Domokos - pharmaexcipients.com
Innovation in the pharmaceutical industry has been limited to the research and development
of new drug products, meanwhile the structure of the production has not changed in …