Age‐related changes in cerebrovascular health and their effects on neural function and cognition: A comprehensive review

B Zimmerman, B Rypma, G Gratton… - …, 2021 - Wiley Online Library
The process of aging includes changes in cellular biology that affect local interactions
between cells and their environments and eventually propagate to systemic levels. In the …

Cerebral blood flow in normal aging adults: cardiovascular determinants, clinical implications, and aerobic fitness

T Tarumi, R Zhang - Journal of neurochemistry, 2018 - Wiley Online Library
Senescence is a leading cause of mortality, disability, and non‐communicable chronic
diseases in older adults. Mounting evidence indicates that the presence of cardiovascular …

[HTML][HTML] Regular walking breaks prevent the decline in cerebral blood flow associated with prolonged sitting

SE Carter, R Draijer, SM Holder… - Journal of applied …, 2018 - journals.physiology.org
Decreased cerebrovascular blood flow and function are associated with lower cognitive
functioning and increased risk of neurodegenerative diseases. Prolonged sitting impairs …

Aerobic exercise improves cognition and cerebrovascular regulation in older adults

V Guadagni, LL Drogos, AV Tyndall, MH Davenport… - Neurology, 2020 - neurology.org
Objective To test the hypothesis that aerobic exercise is associated with improvements in
cognition and cerebrovascular regulation, we enrolled 206 healthy low-active middle-aged …

[HTML][HTML] Exercise for brain health: an investigation into the underlying mechanisms guided by dose

DF Cabral, J Rice, TP Morris, T Rundek… - …, 2019 - Elsevier
There is a strong link between the practice of regular physical exercise and maintenance of
cognitive brain health. Animal and human studies have shown that exercise exerts positive …

The effect of exercise on cerebral blood flow and executive function among young adults: a double-blinded randomized controlled trial

J Liu, L Min, R Liu, X Zhang, M Wu, Q Di, X Ma - Scientific Reports, 2023 - nature.com
Studies have demonstrated that exercise benefits executive function. However, it remains
unclear which type of exercise is optimal for preserving executive function among young …

Elevated aerobic fitness sustained throughout the adult lifespan is associated with improved cerebral hemodynamics

DM Bailey, CJ Marley, JV Brugniaux, D Hodson… - Stroke, 2013 - ahajournals.org
Background and Purpose—Age-related impairments in cerebral blood flow and
cerebrovascular reactivity to carbon dioxide (CVRCO2) are established risk factors for stroke …

Higher levels of cardiovascular fitness are associated with better executive function and prefrontal oxygenation in younger and older women

O Dupuy, CJ Gauthier, SA Fraser… - Frontiers in human …, 2015 - frontiersin.org
Aim: Many studies have suggested that physical exercise training improves cognition and
more selectively executive functions. There is a growing interest to clarify the …

On the run for hippocampal plasticity

HY Moon, H van Praag - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
Accumulating research in rodents and humans indicates that exercise benefits brain function
and may prevent or delay onset of neurodegenerative conditions. In particular, exercise …

Regulation of the cerebral circulation by arterial carbon dioxide

RL Hoiland, JA Fisher, PN Ainslie - Comprehensive physiology, 2011 - Wiley Online Library
Intact, coordinated, and precisely regulated cerebrovascular responses are required for the
maintenance of cerebral metabolic homeostasis, adequate perfusion, oxygen delivery, and …