Serrated lesions of the colorectum: review and recommendations from an expert panel

DK Rex, DJ Ahnen, JA Baron, KP Batts… - Official journal of the …, 2012 - journals.lww.com
Serrated lesions of the colorectum are the precursors of perhaps one-third of colorectal
cancers (CRCs). Cancers arising in serrated lesions are usually in the proximal colon, and …

Terminology, molecular features, epidemiology, and management of serrated colorectal neoplasia

SD Crockett, ID Nagtegaal - Gastroenterology, 2019 - Elsevier
In addition to the adenoma to carcinoma sequence, colorectal carcinogenesis can occur via
the serrated pathway. Studies have focused on clarification of categories and molecular …

Colorectal cancer statistics, 2020

RL Siegel, KD Miller, A Goding Sauer… - CA: a cancer journal …, 2020 - Wiley Online Library
Colorectal cancer (CRC) is the second most common cause of cancer death in the United
States. Every 3 years, the American Cancer Society provides an update of CRC occurrence …

Colorectal cancer statistics, 2023

RL Siegel, NS Wagle, A Cercek… - CA: a cancer journal …, 2023 - Wiley Online Library
Colorectal cancer (CRC) is the second most common cause of cancer death in the United
States. Every 3 years, the American Cancer Society provides an update of CRC statistics …

Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials

PM Rothwell, M Wilson, CE Elwin, B Norrving, A Algra… - The Lancet, 2010 - thelancet.com
Background High-dose aspirin (≥ 500 mg daily) reduces long-term incidence of colorectal
cancer, but adverse effects might limit its potential for long-term prevention. The long-term …

Role of the serrated pathway in colorectal cancer pathogenesis

B Leggett, V Whitehall - Gastroenterology, 2010 - Elsevier
The “serrated neoplastic pathway” describes the progression of serrated polyps, including
sessile serrated adenomas and traditional serrated adenomas, to colorectal cancer. The …

[PDF][PDF] Risk factors for colorectal polyps and cancer

JA Sninsky, BM Shore, GV Lupu, SD Crockett - … Endoscopy Clinics of North …, 2022 - Elsevier
The strongest nonmodifiable risk factors for CRC and precancerous polyps are age, male
sex, and family history of CRC. Current evidence indicates that smoking, obesity, and diet …

The rising incidence of younger patients with colorectal cancer: questions about screening, biology, and treatment

LC Connell, JM Mota, MI Braghiroli, PM Hoff - Current treatment options in …, 2017 - Springer
Opinion statement Colorectal cancer (CRC) is the third leading cancer diagnosed globally
and an important cause of cancer-related mortality. Of interest, while we have witnessed a …

Association between risk factors for colorectal cancer and risk of serrated polyps and conventional adenomas

X He, K Wu, S Ogino, EL Giovannucci, AT Chan… - Gastroenterology, 2018 - Elsevier
Background & Aims Serrated polyps (SPs) and conventional adenomas are precursor
lesions for colorectal cancer (CRC), but they are believed to arise via distinct pathways. We …

Lifestyle risk factors for serrated colorectal polyps: a systematic review and meta-analysis

L Bailie, MB Loughrey, HG Coleman - Gastroenterology, 2017 - Elsevier
Background & Aims Certain subsets of colorectal serrated polyps (SP) have malignant
potential. We performed a systematic review and meta-analysis to investigate the …