Alpha-synuclein research: defining strategic moves in the battle against Parkinson's disease

LMA Oliveira, T Gasser, R Edwards… - npj Parkinson's …, 2021 - nature.com
With the advent of the genetic era in Parkinson's disease (PD) research in 1997, α-synuclein
was identified as an important player in a complex neurodegenerative disease that affects> …

Subtypes of Parkinson's disease: what do they tell us about disease progression?

SM Fereshtehnejad, RB Postuma - Current neurology and neuroscience …, 2017 - Springer
Parkinson's disease is a widely heterogeneous disorder with a broad list of motor and
nonmotor manifestations. Identifying subtypes of Parkinson's disease is one of the top …

Genetic architecture of Parkinson's disease subtypes–Review of the literature

J Dulski, RJ Uitti, OA Ross, ZK Wszolek - Frontiers in aging …, 2022 - frontiersin.org
The heterogeneity of Parkinson's disease (PD) has been recognized since its description by
James Parkinson over 200 years ago. The complexity of motor and non-motor PD …

Pathological influences on clinical heterogeneity in Lewy body diseases

DG Coughlin, HI Hurtig, DJ Irwin - Movement Disorders, 2020 - Wiley Online Library
ABSTRACT PD, PD with dementia, and dementia with Lewy bodies are clinical syndromes
characterized by the neuropathological accumulation of alpha‐synuclein in the CNS that …

Finding useful biomarkers for Parkinson's disease

AS Chen-Plotkin, R Albin, R Alcalay… - Science translational …, 2018 - science.org
Finding useful biomarkers for Parkinson’s disease | Science Translational Medicine news
careers commentary Journals Science Science brought to you byGoogle Indexer Log in science …

Species and cell-type properties of classically defined human and rodent neurons and glia

X Xu, EI Stoyanova, AE Lemiesz, J ** using clinical features and biomarkers: literature review and preliminary study of subtype clustering
SH Lee, SM Park, SS Yeo, O Kwon, MK Lee, H Yoo… - Diagnostics, 2022 - mdpi.com
The second most common progressive neurodegenerative disorder, Parkinson's disease
(PD), is characterized by a broad spectrum of symptoms that are associated with its …