Stimuli-responsive polysaccharide-based smart hydrogels for diabetic wound healing: Design aspects, preparation methods and regulatory perspectives

T Kolipaka, G Pandey, N Abraham… - Carbohydrate …, 2024 - Elsevier
Diabetes adversely affects wound-healing responses, leading to the development of chronic
infected wounds. Such wound microenvironment is characterized by hyperglycaemia …

Poly(N-isopropylacrylamide)-Based Hydrogels for Biomedical Applications: A Review of the State-of-the-Art

MJ Ansari, RR Rajendran, S Mohanto, U Agarwal… - Gels, 2022 - mdpi.com
A prominent research topic in contemporary advanced functional materials science is the
production of smart materials based on polymers that may independently adjust their …

Poly (N-isopropylacrylamide)-based thermoresponsive composite hydrogels for biomedical applications

X Xu, Y Liu, W Fu, M Yao, Z Ding, J Xuan, D Li, S Wang… - Polymers, 2020 - mdpi.com
Poly (N-isopropylacrylamide)(PNIPAM)-based thermosensitive hydrogels demonstrate great
potential in biomedical applications. However, they have inherent drawbacks such as low …

Recent advances in thermo-sensitive hydrogels for drug delivery

Y Yu, Y Cheng, J Tong, L Zhang, Y Wei… - Journal of Materials …, 2021 - pubs.rsc.org
Hydrogels are cross-linked hydrophilic macromolecules that contain a certain amount of
water. Due to their biocompatible, highly tunable and hydrophilic nature, hydrogels have …

Stimulus-responsive hydrogels: Theory, modern advances, and applications

MC Koetting, JT Peters, SD Steichen… - Materials Science and …, 2015 - Elsevier
Over the past century, hydrogels have emerged as effective materials for an immense variety
of applications. The unique network structure of hydrogels enables very high levels of …

[HTML][HTML] Injectable hydrogels in central nervous system: Unique and novel platforms for promoting extracellular matrix remodeling and tissue engineering

E Hasanzadeh, A Seifalian, A Mellati, J Saremi… - Materials Today Bio, 2023 - Elsevier
Repairing central nervous system (CNS) is difficult due to the inability of neurons to recover
after damage. A clinically acceptable treatment to promote CNS functional recovery and …

Polymers exhibiting lower critical solution temperatures as a route to thermoreversible gelators for healthcare

MT Cook, P Haddow, SB Kirton… - Advanced Functional …, 2021 - Wiley Online Library
The ability to trigger changes to material properties with external stimuli, so‐called “smart”
behavior, has enabled novel technologies for a wide range of healthcare applications …

Smart injectable hydrogels for cancer immunotherapy

Y Chao, Q Chen, Z Liu - Advanced Functional Materials, 2020 - Wiley Online Library
Hydrogels, a class of materials with a 3D network structure, are widely used in various fields
especially in biomedicine. Injectable hydrogels could facilitate the encapsulation and …

Hydrogels in a historical perspective: From simple networks to smart materials

SJ Buwalda, KWM Boere, PJ Dijkstra, J Feijen… - Journal of controlled …, 2014 - Elsevier
Over the past decades, significant progress has been made in the field of hydrogels as
functional biomaterials. Biomedical application of hydrogels was initially hindered by the …

Thermoresponsive hydrogels in biomedical applications: A seven-year update

L Klouda - European Journal of Pharmaceutics and …, 2015 - Elsevier
Thermally responsive hydrogels modulate their gelation behavior upon temperature change.
Aqueous solutions solidify into hydrogels when a critical temperature is reached. In …